Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

All subjects will be treated with Interstitial Laser Therapy (ILT) followed by excision no later than 28 days post ablation.

Image guided Interstitial Laser Ablation of breast tumors

Novilase Interstitial Laser Therapy

Barbara Schwartzberg, MD

Michael Shere, M.D.

This study will determine the rate of complete tumor ablation of small breast cancers (≤ 20mm) by Novilase Interstitial Laser Therapy (ILT), and determine the sensitivity and specificity of imaging (MRI, mammography and ultrasound) in detecting residual tumor post ILT ablation as correlated to histopathology from the post-ablation excision.

A Multicenter "Ablate and Resect" Study of Novilase® Interstitial Laser Therapy for the Ablation of Small Breast Cancers

Evaluate the rate of complete tumor ablation by Novilase ILT of small breast cancers and characterize the correlation of imaging (MR, US, x-ray) in detecting residual post ablation with histopathology of the excised specimen.

An individual patient will be considered to have a complete ablation if the pathology results post excision demonstrates that no visible gross residual tumor is present.

Evaluate satisfaction, utilizing the European Organization for Research and Treatment of Cancer Breast Cancer Specific Quality of Life Questionnaire (EORTC QLQ-BR23) survey and cosmetic outcome utilizing the physician-reported Four-Point Scoring System of Breast Cosmesis.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
A Multicenter "Ablate and Resect" Study of Novilase® Interstitial Laser Therapy for the Ablation of Small Breast Cancers	NCT01478438	Malignant Tumor	Novilase Inters...	18 Years - 80 Years	Novian Health Inc.
A Multicenter "Ablate and Resect" Study of Novilase® Interstitial Laser Therapy for the Ablation of Small Breast Cancers	NCT01478438	Malignant Tumor	Novilase Inters...	18 Years - 80 Years	Novian Health Inc.

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