Digestive System Diseases

All Conditions

Symptoms and General Pathology

Inflammatory Bowel Diseases

Diverticulitis

Intestinal Diseases

Gastrointestinal Diseases

Gastroenteritis

Diverticulum

Diverticular Diseases

Central Nervous System Depressants

All Drugs and Chemicals

Anti-Arrhythmia Agents

Channel Blockers

Analgesics

Herbal and Botanical

Anesthetics

Lidocaine

Bupivacaine

Morphine

Anesthetics, Local

Sodium Channel Blockers

Diuretics, Potassium Sparing

Cola

Beside general anesthesia, patients will receive intravenous lidocaine bolus 1.5 mg/kg just prior induction and an infusion of lidocaine 2mg/kg/h will be started and maintained during the whole surgical procedure. Entering the recovery room, this infusion will be decreased at the rate of 1mg/kg/hour for the 48 first hours

Beside general anesthesia, patient will receive epidural freezing medication for 48 hours.

0.1% Epidural bupivacaine + Morphine 0.02 mg/ml drip via epidural x48 hr

Thoracic epidural block

Mingkwan Wongyingsinn, Fellow

Patients receiving perioperative intravenous lidocaine, post operative restoration of bowel movement will be faster and decrease pain intensity, opioid consumption and side effects, length of hospital stay; probably as a result of a significant opioid sparing and attenuated inflammatory response.

The aim of this study is to assess whether perioperative intravenous lidocaine has an impact on the early postoperative physical activity recovery of patients scheduled for laparoscopic colorectal resection.

The study focuses on patients with colorectal disease, which receive the laparoscopic (assisted) surgical approach.

It is hypothesized that in those patients receiving perioperative and post-operative intravenous lidocaine, bowel function recovery will be faster, probably as a result of a significant opioid sparing, less pain and attenuated inflammatory response.

Bowel Function After Laparoscopic Colon Surgery: Effect of IV Lidocaine

Restoration of Bowel Function After Laparoscopic Colorectal Surgery: Effect of Intravenous Lidocaine

Visual analog score pain (from 0-10) at rest, on walking and coughing at 24, 48 and 72 hours after an operation are assessed.

McGill University Health Centre/Research Institute of the McGill University Health Centre

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Bowel Function After Laparoscopic Colon Surgery: Effect of IV Lidocaine	NCT01155440	Colon Cancer Inflammatory Bo... Diverticulitis	Lidocaine Thoracic epidur...	18 Years -	McGill University Health Centre/Research Institute of the McGill University Health Centre
Bowel Function After Laparoscopic Colon Surgery: Effect of IV Lidocaine	NCT01155440	Colon Cancer Inflammatory Bo... Diverticulitis	Lidocaine Thoracic epidur...	18 Years -	McGill University Health Centre/Research Institute of the McGill University Health Centre

Spots Global Cancer Trial Database for 60 patients scheduled to have a colorectal surgery