Neoplasms

All Conditions

Digestive System Diseases

Gland and Hormone Related Diseases

Symptoms and General Pathology

Rare Diseases

Carcinoma

Pancreatic Neoplasms

Neoplasm Metastasis

Liver Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Pancreatic Cancer

Antineoplastic Agents

All Drugs and Chemicals

Hematinics

Gemcitabine

Paclitaxel

Albumin-Bound Paclitaxel

Oxaliplatin

Liver Extracts

Antimetabolites

In 30min after chemotherapy, inject ultrasonic microbubbles 1 ml once and inject 5 times in 20min and locate the ultrasonic probe on the lesion The chemotherapy of pancreatic is gemcitabine.The chemotherapy of liver metastases is oxaliplatin with taxol.

inject 1ml once and five times in 20min, locate the probe on the lesion at the same time

ultrasonic microbubbles

Chemotherapy drug of pancreatic carcinoma is gemcitabine. Chemotherapy drug of liver metastases is oxaliplatin and taxol.

platinum and gemcitabine

Yang Wei, Doctor

Yanjie Wang, Doctor

Wei Yang, Doctor

Yan Li, Doctor

Jifang Gong, Doctor

Kun Yan, Master

Lin Shen, Doctor

Ultrasonic sonoporation can increase the release of chemotherapeutics, thus increasing the therapeutic effects. The main purpose is to identify the safety of combining ultrasonic microbubbles and chemotherapeutics to treat malignant neoplasms of hepatic metastases from alimentary system and pancreatic carcinoma.

Ultrasonic sonoporation can increase the release of chemotherapeutics, thus increasing the therapeutic effects.

1. Main purpose

   1. To identify the safety of combining ultrasonic microbubbles and chemotherapeutics to treat malignant neoplasms of hepatic metastases from alimentary system and pancreatic carcinoma.
   2. To explore the largest mechanical index and ultrasonic treatment time which patients can endure.
2. Secondary purpose

   1. To observe tumor clinical benefit rate (CR+PR+SD).
   2. To evaluate the preliminary effect,such as time to failure(TTF), time to death(TTD)

Safety Study of Combining Ultrasound Microbubbles and Chemotherapy to Treat Malignant Neoplasms of Digestive System

Safety Study of Combining Ultrasound Microbubbles and Chemotherapy to Treat Malignant Neoplasms of Liver Metastases From Gastrointestinal Tumors and Pancreatic Carcinoma

Peking University Cancer Hospital & Institute

chief director

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Safety Study of Combining Ultrasound Microbubbles and Chemotherapy to Treat Malignant Neoplasms of Digestive System	NCT02233205	Gastrointestina...	ultrasonic micr... platinum and ge...	18 Years - 75 Years	Peking University Cancer Hospital & Institute
Safety Study of Combining Ultrasound Microbubbles and Chemotherapy to Treat Malignant Neoplasms of Digestive System	NCT02233205	Gastrointestina...	ultrasonic micr... platinum and ge...	18 Years - 75 Years	Peking University Cancer Hospital & Institute

Spots Global Cancer Trial Database for alimentary

Every month we try and update this database with for alimentary cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for alimentary

Every month we try and update this database with for alimentary cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for alimentary cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.