Symptoms and General Pathology

All Conditions

Behaviors and Mental Disorders

Fatigue

Quality of Life

The research study procedures include screening for eligibility and study treatment including evaluations and follow up visits.

* Patients will attend the 16-week program of boxing conditioning.
* This 16-week program will include supervised exercises designed to improve strength, flexibility, balance,and cardiopulmonary fitness.
* There will be 4, 1-hour sessions each week per participant

H4H fitness program

Elizabeth O'Donnell, MD

This research study is assessing the effect of an exercise program on cancer survivors.

The exercise program is Haymakers for Hope 16-week exercise program

This is a pilot study, it is the first time investigators are examining the effect of this exercise program on cancer survivors physical and emotional functioning. The exercise programs is based on the conditioning program used by boxers.- Haymakers for Hope 16-week exercise program

* The research study procedures include screening for eligibility and study treatment including evaluations and follow up visits.
* Participants will attend the 16-week program of boxing conditioning. It is expected that about 10 people will take part in this research study.

  * This 16 week will include supervised exercises designed to improve strength, flexibility, balance and cardiopulmonary fitness.
  * There will be 4 sessions of 1 hour each week for each of the 10 participants.
  * The program will be conducted at gymnasiums contracted with the H4H program and outcomes assessments at Massachusetts General Hospital and the gymnasiums..

Pilot Study of the Haymakers for Hope Fitness Program

A Pilot Study to Assess the Haymakers for Hope Fitness Program in Cancer Survivors

Participants will be considered to have completed the fitness program if they attend at least 70% of the sessions

Feasibility will be demonstrated if ≥60% of participants complete the fitness program

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Summarize changes from the baseline to follow-up assessment including calculation of the effect size (mean within-subject difference divided by standard deviation of differences). (total cholesterol: mg/dL; triglycerides: mg/dL; high-density lipoprotein cholesterol mg/dL; low-density lipoprotein cholesterol mg/dL; very low-density lipoprotein cholesterol: mg/dL; cholesterol/HDL ratio mg/dL).

Summarize changes from the baseline to follow-up assessment including calculation of the effect size (mean within-subject difference divided by standard deviation of differences), hemoglobin A1c reported as percentage of average blood sugar level (mg/dL or mmol/L), higher % corresponds to higher average blood sugar levels (normal A1C level is below 5.7%)

Summarize changes from the baseline to follow-up assessment including calculation of the effect size (mean within-subject difference divided by standard deviation of differences), mg/L (hs-CRP level of 1 mg/L or lower indicates low risk of CVD, hs-CRP level of 1-3 mg/L indicates moderate risk of CVD, hs-CRP level of greater than 3 mg/L indicates high risk of CVD)

Summarize changes from the baseline to follow-up assessment including calculation of the effect size (mean within-subject difference divided by standard deviation of differences), pg/mL

Summarize changes from the baseline to follow-up assessment including calculation of the effect size (mean within-subject difference divided by standard deviation of differences) (mcU/mL)

Summarize changes from the baseline to follow-up assessment including calculation of the effect size (mean within-subject difference divided by standard deviation of differences) (ng/mL)

Summarize changes from the baseline to follow-up assessment including calculation of the effect size (mean within-subject difference divided by standard deviation of differences) (microgram/mL)

Summarize changes from the baseline to follow-up assessment including calculation of the effect size (mean within-subject difference divided by standard deviation of differences). Plasma glucose: mmol/L (or mg/dL), Insulin: pmol/L (or microunits/mL)

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Pilot Study of the Haymakers for Hope Fitness Program	NCT04220216	Cancer Exercise Test Fatigue Mood Quality of Life Biomarkers	H4H fitness pro...	18 Years -	Massachusetts General Hospital
Pilot Study of the Haymakers for Hope Fitness Program	NCT04220216	Cancer Exercise Test Fatigue Mood Quality of Life Biomarkers	H4H fitness pro...	18 Years -	Massachusetts General Hospital

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