The intervention arm will receive a 12 month mobile health (mHealth) physical activity intervention with a goal of increasing their moderate-vigorous intensity physical activity levels by 90 minutes per week above baseline

Controls will receive general health education materials

The intervention includes a physical activity prescription, a Polar activity tracker watch, access to a private AYA cancer survivor community through the Polar Flow community platform, mHealth nudges and surveys via text messaging, and regular phone or email contact from study staff.

Physical Activity

Leanne Dickau

Pamela Round

Miranda Fidler-Benaoudia

Christine Friedenreich

In this randomized controlled trial the investigators will determine whether a mobile health intervention can increase physical activity levels in AYA cancer survivors over a one year period. The investigators will recruit 320 cancer survivors in Alberta who were diagnosed with a first cancer between the ages of 15 to 39 years and are within one year of treatment completion. Participants will be randomized into either the control group (educational information) or the intervention group (educational information; personalized physical activity plan; activity tracker watch; access to a private, online survivor community; motivational text messages and check-in calls/e-mails). All participants will complete fitness testing and questionnaires at baseline, 6 months and 12 months. A final measurement at 24 months will test long-term effectiveness.

Background:

There is a need for adolescent and young adult (AYA) cancer research because the number of new cancers in young people is increasing and the survivor population is growing. Interventions that try to reduce problems that affect people after cancer are particularly important since its treatments can have negative effects on survivors' physical and mental health even decades after diagnosis.

Aim:

Given the many positive effects of physical activity (e.g. improved fitness and quality of life), the study aims to encourage AYA cancer survivors to be more physically active as they shift from treatment to survivorship care. The main goal of this study is to see if a home-based, mobile health (mHealth) physical activity intervention can increase physical activity levels by at least 90 minutes/week compared to baseline in AYA cancer survivors.

Methods:

The investigators will conduct a two-center randomized controlled trial of 320 AYA cancer survivors. Participants (N=320) will be Albertan residents, diagnosed with a first cancer between the ages of 15 and 39 years, and within one year of cancer treatment completion. At the start of the study, participants will complete fitness testing and questionnaires. Participants will then be randomly put into either a control or intervention group. The control group will receive educational information only. The intervention group will also receive a personalized physical activity plan, an activity tracker watch, access to a private, online survivor community, motivational text messages and check-in calls/e-mails. Fitness testing and questionnaires will be repeated at 6 and 12 months to see if the intervention increased physical activity levels and improved health outcomes among the participants in the intervention group compared to controls. A final measurement at 24 months will test long-term use.

The study team, with the exception of the study coordinator, will be blinded to reduce bias.

mHealth Physical Activity Intervention for Young Cancer Survivors

Adolescents and Young Adults Becoming Physically Active After Cancer Trial

Global score range is 0 to 23 where higher scores indicate worse sleep quality

Measured by combining height (meters) and weight (kilograms) and reported in kg/m2

Measured by peak oxygen consumption in relative (ml/kg/min) values using the incremental Balke and Ware treadmill test with direct measures of gas exchange and ventilation

Measured by peak oxygen consumption in absolute (L/min) values using the incremental Balke and Ware treadmill test with direct measures of gas exchange and ventilation

Measured in kilograms using a hand dynamometer

Measured in kilograms using an 8-10 repetition maximum (RM) chest press test used to predict 1-RM

Measured in kilograms using the maximum number of chest press repetitions completed at 50-70% of estimated 1-RM

Measured in kilograms using an 8-10 repetition maximum (RM) leg press test used to predict 1-RM

Measured in kilograms using the maximum number of leg press repetitions completed at 50-70% of estimated 1-RM

Defined according to the Fried phenotype which takes into account low lean muscle mass, exhaustion, low energy expenditure, walking limitations, and weakness

Score range is from 0 to 100 where higher scores indicate better mental health

Score range is from 0 to 100 where higher scores indicate better physical health

Score range is from 0 to 100 where higher scores indicate higher functioning

Score range is from 0 to 100 where higher scores indicate less pain

Score range is from 0 to 100 where higher scores indicate better health

Score range is from 0 to 100 where higher scores indicate higher vitality

Scores range from 0 to 100 where higher scores indicate more distress

Score range is from 0 to 80. Higher scores indicate poorer quality of life.

Score range is from 0 to 16 where higher scores indicate poorer cognition

Score range is from 0 to 36 where higher scores indicate poorer cognition

Score range is from 0 to 52 where higher scores indicate less fatigue

Score range is from 0 to 44 where higher scores indicate better financial wellbeing

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
mHealth Physical Activity Intervention for Young Cancer Survivors	NCT04765241	Cancer	Physical Activi...	15 Years - 39 Years	AHS Cancer Control Alberta
mHealth Physical Activity Intervention for Young Cancer Survivors	NCT04765241	Cancer	Physical Activi...	15 Years - 39 Years	AHS Cancer Control Alberta

Spots Global Cancer Trial Database for aya cancer

Every month we try and update this database with for aya cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for aya cancer

Every month we try and update this database with for aya cancer cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for aya cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.