Gastrointestinal Agents

All Drugs and Chemicals

Herbal and Botanical

Pancrelipase

Pancreatin

Cola

Participants will be robotic surgeons in urologic, gynecologic, colorectal, hepatobiliary, gastric, and thoracic surgery

Surgeons will perform and participants will undergo robotic surgery according to the standard of care. No additional interventions will be performed on participating participants.

Robotic Surgery

Alvin Goh, MD

The purpose of this study is to develop new tools to understand surgeon performance to improve surgical training and participant outcomes after surgery.

Improving Surgeon Performance Measures for Robot-Assisted Surgery

Generalized Robotic Skills Assessment Using Machine Learning-Based Analysis Across Multiple Surgical Specialties

Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made following one year after publication and for up to 36 months later. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.

For the primary objective, we will capture Automated Performance Metrics/APMs and will determine the association between these and other metrics and surgeon experience, which will be used to construct validation.

APMs that will be used in the study:

Time Metrics

Camera Metrics

Instrument Metrics

System Metrics

Articulation Metrics

Memorial Sloan Kettering Cancer Center

Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Urinary Bladder Neoplasms

Urologic Neoplasms

Urogenital Neoplasms

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Urinary Bladder Diseases

Urologic Diseases

Male Urogenital Diseases

During bladder cancer surgery, whole genome gene expression array assays obtained on tumor biopsy specimens. Analysis to determine biologic subtypes which will then be correlated with final pathology, identifying the subtype(s) associated with noc-MIBC. 3 Tesla pelvic magnetic resonance imaging (MRI) performed four weeks after bladder cancer surgery.

During bladder cancer surgery, tissue specimen taken for molecular profiling.

Tissue Biopsy

3 Tesla pelvic magnetic resonance imaging (MRI) performed four weeks after bladder cancer surgery.

Magnetic Resonance Imaging (MRI)

Neema Navai, MD

The goal of this research study is to improve detection of cancer outside of the bladder through genetic testing and improved imaging.

If participant agrees to take part in the study, a piece of the tumor that is removed during the biopsy will be collected for research purposes. The tissue will be sent to the laboratory for genetic testing.

If they have had a computed tomography scan (CT scan) or magnetic resonance imaging scan (MRI) recently, information collected from the scan will be collected. If they have not had one recently, they will have an MRI with contrast as part of this study. They will receive a separate consent form for this MRI scan.

The results of the test will be given to their doctor, but the results will not be used to decide their treatment.

After they have surgery, information will be collected from their medical records, such as their diagnosis.

Length of Study:

* Their participation on this study will be over once their surgery is completed.
* This is an investigational study.

Up to 100 participants will take part in this study. All will be enrolled at MD Anderson.

At the time of biopsy, a portion of the fresh human tumor biopsy samples utilized for DNA and RNA extraction.

Improving Clinical Staging for Muscle Invasive Bladder Cancer Through Molecular Profiling and Improved Imaging

Improved cross sectional imaging with pelvic MRI, and biopsy specimen molecular profiling used to identify muscle invasive bladder cancer (noc-MIBC). Analysis to determine biologic subtypes which will then be correlated with final pathology, identifying the subtype(s) associated with noc-MIBC.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Improving Surgeon Performance Measures for Robot-Assisted Surgery	NCT06037837	Surgery	Robotic Surgery	18 Years -	Memorial Sloan Kettering Cancer Center
Improving Clinical Staging for Muscle Invasive Bladder Cancer Through Molecular Profiling and Improved Imaging	NCT02203136	Bladder Cancer	Tissue Biopsy Magnetic Resona...	-	M.D. Anderson Cancer Center
Improving Clinical Staging for Muscle Invasive Bladder Cancer Through Molecular Profiling and Improved Imaging	NCT02203136	Bladder Cancer	Tissue Biopsy Magnetic Resona...	-	M.D. Anderson Cancer Center

Spots Global Cancer Trial Database for bladder surgery