Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Rare Diseases

Melanoma

Skin Neoplasms

Hemangiosarcoma

Neuroendocrine Tumors

Neuroectodermal Tumors

Neuroectodermal Tumors, Primitive

Neoplasms, Germ Cell and Embryonal

Neoplasms by Histologic Type

Neoplasms, Nerve Tissue

Nevus, Pigmented

Nevus

Nevi and Melanomas

Skin Diseases

Sarcoma

Neoplasms, Connective and Soft Tissue

Neoplasms, Vascular Tissue

Neuroendocrine Tumor

Neuroepithelioma

Soft Tissue Sarcoma

Micronutrients

All Drugs and Chemicals

Boron

BNCT(Boron Neutron Capture Therapy)

SPM-011 iv administrates at 200 mg/kg/hr for 2 hours before neutron irradiation. During neutoron irradiation with CICS-1, SPM-011 iv continues at 100mg/kg/hr.

Intravenous administration of SPM-011 and neutron irradiation with CICS-1.

CICS-1 (investigational device),SPM-011(investigational drug)

Among skin malignancies, patients with malignant melanoma or angiosarcoma are treated with BNCT using CICS-1 and SPM-011 (borofalan (10B)). Through this trial, safety and appropriate treatment dose will be determined.

Boron Neutron Capture Therapy Using CICS-1 and SPM-011 for Malignant Melanoma and Angiosarcoma

Phase 1 Clinical Trial of Boron Neutron Capture Therapy (BNCT) Using CICS-1 and SPM-011 for Malignant Melanoma and Angiosarcoma

Evaluate the safety at each dose level by the frequency of DLT occurrence

Evaluate the incidence of adverse events and failures during the study period

Stella Pharma Corporation

Cancer Intelligence Care Systems, Inc.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Boron Neutron Capture Therapy Using CICS-1 and SPM-011 for Malignant Melanoma and Angiosarcoma	NCT04293289	Malignant Melan... Angiosarcoma	CICS-1 (investi...	20 Years - 85 Years	Cancer Intelligence Care Systems, Inc.
Boron Neutron Capture Therapy Using CICS-1 and SPM-011 for Malignant Melanoma and Angiosarcoma	NCT04293289	Malignant Melan... Angiosarcoma	CICS-1 (investi...	20 Years - 85 Years	Cancer Intelligence Care Systems, Inc.

Spots Global Cancer Trial Database for borofalan

Every month we try and update this database with for borofalan cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for borofalan

Every month we try and update this database with for borofalan cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for borofalan cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.