Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Heart and Blood Diseases

Rare Diseases

Urinary Bladder Neoplasms

Acute Kidney Injury

Hypotension

Vascular Diseases

Acute Graft Versus Host Disease

Central Nervous System Depressants

All Drugs and Chemicals

Anesthetics

Managing intraoperative hemodynamic condition under the HPI guidance

Managing intraoperative hemodynamic condition with standard anesthesia care (blinding the HPI monitor screen)

The hemodynamic condition of the HPI group will be managed by HPI guidance which is derived by arterial pressure waveform information, including Eadyn, SVV, dP/dt.

BP management with HPI guidance

Sooyoung Cho, MD, PhD

It is a single-center randomized controlled trial that aims to figure out the effect of the hypotension prediction index (HPI) on the prevention of acute kidney injury (AKI) after radical cystectomy. The primary hypothesis is that HPI software guidance prevents postoperative AKI by reducing the duration and severity of intraoperative hypotension (IOH).

Hypotension Prediction Effect on AKI

Effect of Use of Hypotension Prediction System in Prevention of Postoperative Acute Kidney Injury in Radical Cystectomy

Occurrence of acute kidney injury after radical cystectomy

Depth and duration of hypotension will be assessed by calculating time weighted average (TWA) of hypotension under mean arterial pressure under 65 mmHg during the operation

Time weighted average of hypotension prediction index during the operation

Ewha Womans University Mokdong Hospital

Assistant Professor

Prostatic Neoplasms

Carcinoma, Renal Cell

Urologic Diseases

Kidney Neoplasms

Urogenital Neoplasms

Urogenital Diseases

Male Urogenital Diseases

Urologic Neoplasms

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Kidney Diseases

Renal Cell Carcinoma

Sooyoung Cho

It is a single-center randomized controlled trial that aims to figure out the effect of the hypotension prediction index (HPI) on the prevention of acute kidney injury (AKI) after robot-assisted urological surgery. The primary hypothesis is that HPI software guidance prevents postoperative AKI by reducing the duration and severity of intraoperative hypotension (IOH).

HPI Effect in Robotic Urological Surgery on AKI

Effect of Use of Hypotension Prediction System in Prevention of Postoperative Acute Kidney Injury in Robotic-assisted Urologic Surgery

Occurrence of acute kidney injury after robotic urological surgery

Biomarkers for early detection of AKI - Cystacin C, KIM-1

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Hypotension Prediction Effect on AKI	NCT04994639	Bladder Cancer	BP management w...	19 Years -	Ewha Womans University Mokdong Hospital
HPI Effect in Robotic Urological Surgery on AKI	NCT06051162	Prostate Cancer Renal Cancer Urologic Diseas...	BP management w...	19 Years -	Ewha Womans University Mokdong Hospital
Hypotension Prediction Effect on AKI	NCT04994639	Bladder Cancer	BP management w...	19 Years -	Ewha Womans University Mokdong Hospital
HPI Effect in Robotic Urological Surgery on AKI	NCT06051162	Prostate Cancer Renal Cancer Urologic Diseas...	BP management w...	19 Years -	Ewha Womans University Mokdong Hospital
Hypotension Prediction Effect on AKI	NCT04994639	Bladder Cancer	BP management w...	19 Years -	Ewha Womans University Mokdong Hospital

Spots Global Cancer Trial Database for bp management with hpi guidance