Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

* Total mastectomy + immediate reconstructive surgery
* 6 months after surgery : Functional MRI and questionnaires

* Within 2 months before surgery : Functional MRI
* Reconstructive surgery
* 6 months after surgery : Functional MRI and questionnaires

Functional MRI

Claudia REGIS, MD

Breast reconstruction is an integral part of the management of patients with breast cancer and treated by total mastectomy. The aim of breast reconstruction is to get a satisfying aesthetic and functional result (sensitivity) and that would enable the patient to appropriate the reconstructed breast. Patient satisfaction assessed subjectively by questionnaires would be better in autologous reconstructions than in reconstructions by prosthesis.

The aim of our trial is to use functional MRI (fMRI) as an objective evaluation tool to describe the brain functional changes of sensory projections after immediate or secondary breast reconstruction.

Patients responding criteria for selection and not objecting to participate in this trial will address a quality of life questionnaire at baseline. Then the study procedures differ depending on which group the patient belongs to.

Immediate breast reconstruction group : Six months after surgery (or six months after the implantation of the definitive prosthesis in case of use of a tissue expander), a postoperative fMRI will be performed and patients will be asked to complete a quality of life form and a satisfaction form.

Secondary breast reconstruction group :

* In the two months preceding the surgery, a preoperative fMRI will be performed.
* Six months after surgery (or six months after the implantation of the definitive prosthesis in case of use of a tissue expander), a postoperative fMRI will be performed and patients will be asked to complete a quality of life form and a satisfaction form.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Breast Reconstruction and Body Map : Assessment by Functional MRI (REMASCO)	NCT02553967	Breast Cancer	Functional MRI	18 Years -	Centre Oscar Lambret
Breast Reconstruction and Body Map : Assessment by Functional MRI (REMASCO)	NCT02553967	Breast Cancer	Functional MRI	18 Years -	Centre Oscar Lambret

Spots Global Cancer Trial Database for breast q questionnaire