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Cola

Cohort of patients with giant colonic lesions resected by ESD, in which patients will be matched to group B

Cohort of patients who underwent colonic surgery for T1 or T2 or in situ colon cancer

Propose a one-piece endoscopic resection such as endoscopic submucosal dissection (ESD) rather than surgery for benign lesions and superficial T1 cancers colorectal cancers offers comparable efficacy with better tolerability. This approach is all the more in the rectum, even for giant lesions lesions (over 8cm), as rectal surgery is particularly morbid, with particularly morbid, with a functional impact that can impact, whereas rectal ESD is less prone to complications fewer complications than in the colon. Colonic ESD for giant lesions is a longer and more morbid more time-consuming and morbid than for smaller lesions, the question of colonic surgery in this indication. this indication. In order to compare the morbidity data of patients of giant lesions with those of colectomy, a control group colectomy, a surgical control group will be set up, including patients including patients having undergone surgery for in situ T1 or T2 in situ colon cancer. Surgical resections of resection of benign lesions is generally not indicated not indicated and would not provide the necessary necessary for a comparison. T3 and T4 lesions with their own their own morbidity will be excluded.

Comparison of MORbidity of Submucosal DIssection Resection of Giant cOlon Lesions Versus Surgery: a National Multicenter Study (MORDIGO)

Comparison of MORbidity of Submucosal DIssection Resection of Giant cOlon Lesions Versus Surgery: a National Multicenter Study

All collected data that underlie results in a publication

Comparison of severe morbidity (Clavien dindo ≥ IIIb) at 30 days of patients who underwent DSM for giant colonic lesion (group A) to that of patients who underwent surgery surgery equivalent to that which would be performed for such a lesion (group B)

University Hospital, Brest

Symptoms and General Pathology

Behaviors and Mental Disorders

Fatigue

Quality of Life

Patients undergoing laparoscopic colonic surgery are compared with a historical cohort of patients undergoing similar open colonic surgery (right hemicolectomy and sigmoid resections).

Laparoscopic colonic surgery

Martin B Jensen, MD, Ph.d.

Søren Laurberg, Professor

The standard procedure for treating colonic cancer is changing from open surgery to laparoscopic surgery. Following open colonic surgery patients are fatigued and loss body mass and have a reduction in physical function, but the investigators do not know if this is also the case following laparoscopic surgery.

This study examines how fatigue, quality of life, physical function, and body composition changes following laparoscopic colonic surgery.

Patients are examined preoperatively and postoperative day 10 and 30.

Rehabilitation Following Laparoscopic Colonic Surgery

Changes in Fatigue and Physical Function Following Laparoscopic Colonic Surgery

Aarhus University Hospital

Associate Professor, Institute of Public Health Aarhus

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Comparison of MORbidity of Submucosal DIssection Resection of Giant cOlon Lesions Versus Surgery: a National Multicenter Study (MORDIGO)	NCT06371898	Colonic Neoplas...		18 Years -	University Hospital, Brest
Rehabilitation Following Laparoscopic Colonic Surgery	NCT00938210	Colonic Cancer Postoperative C... Fatigue	Laparoscopic co...	-	Aarhus University Hospital
Rehabilitation Following Laparoscopic Colonic Surgery	NCT00938210	Colonic Cancer Postoperative C... Fatigue	Laparoscopic co...	-	Aarhus University Hospital

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