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TEMPO

Aluminum hydroxide, magnesium hydroxide, simethicone drug combination

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Reminder letter for people at high risk of colorectal cancer.

Tempo Colo

France is one of the European countries where the incidence of colorectal cancer is the highest among cancers for both sexes. Fecal occult blood screening has been implemented since 2008. However, this screening excludes high risk people who have a 10 to 30 % risk of developing a CRC during their lifetime. Colonoscopy follow up of these persons is not organized, and it is up to the attending physician to recall the date of the surveillance colonoscopy. This results in a poor compliance with the recommendations by these people. A postal reminder of the surveillance colonoscopies sent by The French screening organizations to the patients should increase adherence to follow-up recommendations. The colorectal cancer screening organizations will collects from the hepatogastroenterologists (HGE) informations on colonoscopies of people more than 50 years old who live in the Rhone. These informations will allow to send a reminder 3 months before the date recommended by the HGE. Participation rate and timeliness will be assessed, as well as the severity of the lesions found. A medico-economic analysis will also be carried out.

A prospective interventional study to evaluate the impact of a reminder sent by the Adémas-69 organization to improve coloscopy surveillance and compliance with recommendations for high risk of colorectal cancer people.

Colorectal Cancer Screening French Organizations for the Follow-up After Colonoscopy

Extending the Prerogatives of Colorectal Cancer Screening French Organizations to the Follow-up After Colonoscopy of Patients Aged 50 or More: Pilot Study in the Rhône Administrative Department

participation rate at future colonoscopy that is the number of patient that really have colonoscopy among the patients who receive a reminder letter The systematic registry of colonoscopies will permit to assess if a patient performs it.

We will assess the severity of the lesions found at colonoscopy performed at th right time : level of dysplasia ; size ; histologic characteristics ; numbers of adenoma.

French Health Insurance is the point of vue selected for the evaluation. It's a cost-utility analysis. A Markov model will be performed. The data will proceed from litterature and from data registration during the study. A complementary study will be performed specifically if needed.

For the Markov model the data needed : neoplasia, adenocarcinoma, advanced adenoma, reminders costs, treatments costs, examinations costs, organization costs.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Colorectal Cancer Screening French Organizations for the Follow-up After Colonoscopy	NCT03383367	Colorectal Canc...	Tempo Colo	50 Years -	Association pour le Dépistage Organisé des Cancers dans le Rhône
Colorectal Cancer Screening French Organizations for the Follow-up After Colonoscopy	NCT03383367	Colorectal Canc...	Tempo Colo	50 Years -	Association pour le Dépistage Organisé des Cancers dans le Rhône
Colorectal Cancer Screening French Organizations for the Follow-up After Colonoscopy	NCT03383367	Colorectal Canc...	Tempo Colo	50 Years -	Association pour le Dépistage Organisé des Cancers dans le Rhône

Spots Global Cancer Trial Database for colonoscopy surveillance