Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Behaviors and Mental Disorders

Breast Neoplasms

Breast Diseases

Skin Diseases

Quality of Life

Women being treated for stage I-III breast cancer who were employed prior to this diagnosis will be recruited in their physicians' offices.

Peer controls will be nominated by participants in the breast cancer survivor group or recruited by community outreach and matched for age, language, and ethnicity. This cohort is no longer recruiting.

Patients will be asked to complete a questionnaire at baseline, and then one at follow up, 3-4 months after treatment completion. The patient will be contacted one and two years after the completion of their follow up questionnaire for a brief one-question survey regarding current employment status. A member of the study team will call a subset of patients who have completed both baseline and follow-up surveys to clarify responses to previous questions. Patients will be considered lost to follow- up if surveys A or C have not been completed two years from the participant's consent date (participants who enroll but do not complete survey A are not prompted for survey C). Deviations will not be filed until the end of the study, as there are opportunities over the course of study follow- up to collect previously missing information.

survey web-based or telephone interview

Patients will be asked to complete a questionnaire at baseline, and then one at follow up, 3-4 months after treatment completion. All three follow-up contact methods (email, postcard, call) contain the same question regarding current employment status with minor modifications in formatting. However, the employment question asked in all three follow-up contact methods is shown in the Postcard_Template document. Due to the recent COVID-19 pandemic study staff will be working from home. Therefore, calls will be made via MSK-approved platforms (e.g. Jabber, etc.). Participants who express concerns or request assistance related to COVID-19 will be referred to publicly available resources as needed (e.g., call 311 for access to health care or food panties, etc.) and will be noted in internal tracking logs. The data collected for these internal tracking logs will be managed through a REDCap database.

Victoria Blinder, M.D., M.Sc.

The purpose of this study is to learn more about how being treated for breast cancer affects patients' employment, financial situation, and quality of life on a short-term basis and on a long term basis. Most studies of employment after breast cancer have focused on Caucasian women.This study will evaluate the impact of breast cancer on the lives of women from different ethnic groups.

Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life

Breast Cancer and the Workforce: Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life (BCW)

The City College of New York

NYC Health & Hospitals/ Lincoln Medical Center

New York Presbyterian Queens

New York City Health and Hospitals Corporation

Queens Medical Associates

Memorial Sloan Kettering Cancer Center

Digestive System Diseases

Gland and Hormone Related Diseases

Rare Diseases

Pancreatic Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Endocrine Gland Neoplasms

Gastrointestinal Diseases

Pancreatic Diseases

Endocrine System Diseases

Pancreatic Cancer

Subjects with pancreatic carcinoma who joined the interview group.

Subjects with pancreatic carcinoma who joined the user testing group

Black subjects with pancreatic cancer will provide insight on their experience discussing clinical trials and preferences for communicating clinical trial information

semistructured interviews

Black subjects with pancreatic cancer will provide feedback on mHealth app prototype.

feedback

Lori Stravers

Brent Henderson

Jen Jen Yeh, MD

Christian Campbell

Ugwuji Maduekwe, MD, MMSc, MPH

Jen J Yeh, MD

To develop a culturally tailored informational mobile application and test whether it will increase participation among Black pancreatic cancer subjects in clinical trial discussions with their care team.

This project aims to identify and address barriers to enrollment of Black subjects in pancreatic cancer clinical trials using a culturally informed mobile health application to promote participation.

The clinical trial education and communication needs of Black people with pancreatic cancer will be determined. A new mHealth application for clinical trial education and communication tailored to subject needs will be developed. It was hypothesized that a culturally tailored informational mobile application will increase the participation of Black subjects in clinical trial discussions with their care team among the target population.

This study focuses on Black pancreatic cancer subjects, who experience higher mortality rates and lower clinical trial participation than White subjects. Research shows that the disparity between clinical trial participation is in part due to inequitable recruitment practices. This study will use mobile application technology (mHealth app) as an educational, communication, audit, and feedback tool to promote patient-initiated clinical trial discussions among Black people with pancreatic cancer and their cancer care team.

There will be 2 groups: 20 subjects with pancreas carcinoma for phone interviews and 6 for user testing the first version of the application..

Promoting CT Engagement for Pancreatic Cancer With App

PROmoting CLinicAl TrIal EngageMent for Pancreatic Cancer App Study (PROCLAIM Study

The clinical trial education and communication needs of Black people with pancreatic cancer will be determined with feedback and qualitative analysis of findings from semi-structured interviews to develop an mHealth application.

Lustgarten Foundation

UNC Lineberger Comprehensive Cancer Center

Symptoms and General Pathology

Disease Susceptibility

Disease Attributes

Breast cancer patients presenting to single center in Karachi over the period of 10 years. The aim was to look for ethnic predisposition of population, age of breast cancer, stage at arrival and menopausal status specific to our population. No intervention done.

Breast Cancer positive patients

Breast cancer, a leading cause of mortality among females, has been the center of research for many decades. Work is in progress to further advance the research worldwide and in our region. This study is conducted to look into regional ethical predilection, clinical presentation/stage, pathological subtypes \& risk factors of BC among patients of Karachi, with the aim of proposing a ground to policy making regarding protocol setting for screening and management of BC for our region.

Background Breast cancer, a leading cause of mortality among females, has been the center of research for many decades. Work is in progress to further advance the research worldwide and in our region. This study is conducted to look into regional ethical predilection, clinical presentation/stage, pathological subtypes \& risk factors of BC among patients of Karachi, with the aim of proposing a ground to policy making regarding protocol setting for screening and management of BC for our region.

Methods A prospective cohort single-centered study conducted, which included 500 female patients who attended one surgical unit of a tertiary care public hospital Karachi, during the period of 2010 - 2020. The study was performed in line with the principles of the Declaration of Helsinki and data collection started after taking hospital ethical review board's approval because personal data of patients was used. Afterwards, informed written consent was taken from every included patient. Prior to collecting data, all researchers were thoroughly trained with regards to data collection and examination of patients to eliminate observer bias. Non probability consecutive sampling technique was used. The allotted patients were followed by same researcher from presentation till the end of follow up to avoid observer bias; through direct patient interaction in OPDs and wards, radiological and histo-pathological results from investigations performed and regular follow up of patients during the complete disease period. The retrieved information was filled on pre designed pro-forma. Patients were preemptively explained about our reason for collecting data and its implications. The study is reported according to STROCSS 2021 guidelines.15 Our inclusion criteria was ; female sex, age ≥ 20 years, patients with availability of complete clinical details, biopsy proven breast cancer, no previous history of breast cancer treatment from other centers, all regional ethnicities(residents of Karachi, Sindh only) and all stages of breast cancer. Exclusion criteria of the study was; previously treated breast cancer patients, recurrent BC, female ≤19 years, male/transgender, females coming for treatment from other provinces/foreigners.

Thorough history of all patients obtained including relevant risk factors; i-e age, family history of BC, marital status, age at first born baby, parity, age of menarche/menopause, socio-economic status and ethnicity. Detailed physical examination including clinical presentation of breast lump, its size, side (right/left breast) and site, nipple discharge, nipple retraction, skin involvement, fixity to underlying structures, and lymph node status, was carried out in each patient by a single examiner. Patients presenting with a discrete lump, nipple discharge, nipple changes, skin changes, palpable axillary lymph nodes were subjected to further investigation. Ultrasonography and mammogram of the breast, where possible, were performed as initial imaging modality. FNAC/Biopsy, was carried out in all patients to confirm the diagnosis of BC, its subtype and receptors status. For staging; x-ray chest, ultrasound abdomen for liver and pelvis/ CT chest \& abdomen were done on case based need. Bone scan was performed in only symptomatic cases. After thorough overall assessment, clinical stage of BC was assigned to each patient, and stage based treatment was carried out in every patient. Patients having localized disease (≤stage 2A) underwent surgical intervention first followed by chemo/radiotherapy, regional disease(≥ stage 2B) had neo-adjuvant followed by surgery, and advanced disease(stage 4) were given palliation.16 Post operatively detailed histological report of specimen and microscopic involvement of the lymph nodes status were also noted.

Primary outcomes of the cohort were age, ethnicity, family history, stage/histological type and menopausal status while secondary outcomes were parity, marriage, symptoms, lump size/site and socioeconomic status. After collecting the required data on pro forma, it was analyzed using descriptive statistics by SPSS version 23.0 software. With sample size of 500, co-operation rate was 100% and our confidence interval was 97.5% with 5% margin of error. For quantitative data, mean and standard deviation were calculated. Qualitative results were calculated in percentages and presented in tabular forms.

Females were included in our study because more than 99% of our patients presenting with breast cancer were females, so we carried out our study on females only due to high prevalence rates

Ethnic Predisposition, Risk Factors & Breast Cancer Presentation.

Ethnic Predisposition, Risk Factors & Breast Cancer Presentation; a 10 Year Data. Single Centered Prospective Cohort Study From Karachi

Age range assessed as compare to other studies and included range from 20 years till 85 years, because majority of cases fall in this category

different ethnic groups residing in Karachi were assessed, based on city population data on different ethnicities living in the city

Staging of the tumor done according to NCCN guidelines

breast cancer subtype identified according to classification data available on subtypes, based on histopathology

family history data acquired by asking direct questions through the patients. One or more positive relatives with breast cancer in the family were labelled as family history positive patients

menopausal status was asked by patients if they not have had their last period since last 12 months. 12 months period criteria was set

secondary outcomes were studied to look for relation of breast cancer with marital status, parity/number of children, symptoms, lump size and site on presentation

Bahria University

Dr Mehwish Mooghal

Heart and Blood Diseases

Musculoskeletal Diseases

Infections

Nutritional and Metabolic Diseases

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Nervous System Diseases

Depression

Hypertension

Heart Diseases

Arthritis

Leiomyoma

Depressive Disorder

Headache

Communicable Diseases

Osteoporosis

Myofibroma

Urinary Tract Infections

Bone Diseases

Bone Diseases, Metabolic

Metabolic Diseases

Pain

Neurologic Manifestations

Urologic Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Male Urogenital Diseases

Neoplasms, Connective and Soft Tissue

Neoplasms by Histologic Type

Vascular Diseases

Fredi Kronenberg, PhD

The purpose of this study is to examine socio-cultural factors of women's use of complementary and alternative medicine (CAM). The effects of socioeconomic status, social networks and acculturation on CAM use will be assessed among white, African-, Mexican-, and Chinese-American women.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life	NCT01134172	Breast Cancer	survey web-base... survey web-base...	18 Years - 64 Years	Memorial Sloan Kettering Cancer Center
Promoting CT Engagement for Pancreatic Cancer With App	NCT06252545	Pancreas Cancer	semistructured ... feedback	18 Years -	UNC Lineberger Comprehensive Cancer Center
Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life	NCT01134172	Breast Cancer	survey web-base... survey web-base...	18 Years - 64 Years	Memorial Sloan Kettering Cancer Center
Ethnic Predisposition, Risk Factors & Breast Cancer Presentation.	NCT05458570	Breast Cancer	Breast Cancer p...	20 Years - 85 Years	Bahria University
Women's Use of Alternative Medicine: A Multiethnic Study	NCT00067249	Uterine Fibroid... Osteoporosis Urinary Tract I... High Blood Pres... Heart Disease Arthritis Depression Headaches		18 Years -	National Center for Complementary and Integrative Health (NCCIH)
Women's Use of Alternative Medicine: A Multiethnic Study	NCT00067249	Uterine Fibroid... Osteoporosis Urinary Tract I... High Blood Pres... Heart Disease Arthritis Depression Headaches		18 Years -	National Center for Complementary and Integrative Health (NCCIH)

Spots Global Cancer Trial Database for ethnicity

Every month we try and update this database with for ethnicity cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for ethnicity

Every month we try and update this database with for ethnicity cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for ethnicity cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.