Neoplasms

Respiratory Tract (Lung and Bronchial) Diseases

All Conditions

Digestive System Diseases

Gland and Hormone Related Diseases

Rare Diseases

Carcinoma, Non-Small-Cell Lung

Lung Neoplasms

Pancreatic Neoplasms

Adenocarcinoma

Carcinoma

Respiratory Tract Neoplasms

Thoracic Neoplasms

Lung Diseases

Respiratory Tract Diseases

Carcinoma, Bronchogenic

Bronchial Neoplasms

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Pancreatic Cancer

MRTX1133 recommended Phase 2 dose administered to separate cohorts of patients with selected solid tumor malignancies with KRAS G12D mutation to include the following: NSCLC, PDAC, CRC, Other Solid Tumors

MRTX1133

Mirati Therapeutics Study Locator Services

Hirak Der-Torossian, MD

A Phase 1/2 study of MRTX1133 in solid tumors harboring a KRAS G12D mutation.

This first-in-human clinical trial will begin with an exploration of MRTX1133 dose and regimen. As potentially viable regimens are identified, Phase 1b expansion cohorts may be implemented to ensure collection of sufficient safety and PK information, and early evidence of clinical activity are available to recommend Phase 2 regimens. In Phase 2, separate cohorts of patients by histological diagnosis and/or baseline characteristics will be evaluated for the clinical activity and efficacy of MRTX1133.

Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation

A Phase 1/2 Multiple Expansion Cohort Trial of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation

Mirati Therapeutics Inc.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation	NCT05737706	Solid Tumor Advanced Solid ... Non-small Cell ... Colo-rectal Can... Pancreatic Aden...	MRTX1133	18 Years -	Mirati Therapeutics Inc.
Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation	NCT05737706	Solid Tumor Advanced Solid ... Non-small Cell ... Colo-rectal Can... Pancreatic Aden...	MRTX1133	18 Years -	Mirati Therapeutics Inc.

Spots Global Cancer Trial Database for g12d

Every month we try and update this database with for g12d cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for g12d

Every month we try and update this database with for g12d cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for g12d cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.