Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Rare Diseases

Hydatidiform Mole

Nevus

Gestational Trophoblastic Disease

Trophoblastic Neoplasms

Neoplasms, Germ Cell and Embryonal

Neoplasms by Histologic Type

Pregnancy Complications

Pregnancy Complications, Neoplastic

Urogenital Diseases

Female Urogenital Diseases

Female Urogenital Diseases and Pregnancy Complications

Vasodilator Agents

All Drugs and Chemicals

Nitroglycerin

In single evacuation group women will be treated by suction evacuation and curettage is performed at the end of evacuation in one sitting. An ultrasound will be done later to examine completeness of evacuation. If there is significant amount of residual molar tissue or persistence of heavy bleeding a repeat curettage will be done . Women will be followed up with serum beta hcg 1 week after the evacuation and then weekly till the titer is negative. After three consecutive negative titre beat HCG estimation will be done at two weekly interval.

Suction and evacuation

In double evacuation group , women will be treated by suction evacuation and a thorough curettage will be avoided. A second evacuation with thorough curettage will be performed after 5 - 7 days of first evacuation.

Snehamay Chaudhuri, MD, DNB

Hydatidiform mole is a common complication of pregnancy with an incidence of 1in 400 pregnancies in India. Although this is a benign condition , it is having the malignant potential too. A repeat curettage after evacuation of hydatidiform mole was generally advocated till 1990s. A thorough curettage at the time of initial evacuation was not performed because of larger size of uterus and risk of perforation. Subsequently a number of studies assessed the usefulness of repeat curettage and found it was unnecessary and not cost effective . However all these studies are retrospective in design and conducted in developed countries where hydatidiform mole is diagnosed earlier because of wider use of ultrasonography. Thus there is a need to perform a well designed prospective study to compare the effectiveness of single evacuation with double evacuation in treatment of hydatidiform mole for prevention of Gestational Trophoblastic Neoplasia.This study compares the effectiveness of single evacuation versus double evacuation for treatment of hydatidiform mole for prevention of gestational trophoblastic neoplasia .

A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform Mole

A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform

Nilratan Sircar Medical College

Associate Professor,Obstetrics and Gynecology, NRS Medical College

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform Mole	NCT01630954	Hydatidiform Mo...	Suction and eva... Suction and eva...	15 Years - 45 Years	Nilratan Sircar Medical College
A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform Mole	NCT01630954	Hydatidiform Mo...	Suction and eva... Suction and eva...	15 Years - 45 Years	Nilratan Sircar Medical College

Spots Global Cancer Trial Database for h mole

Every month we try and update this database with for h mole cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for h mole

Every month we try and update this database with for h mole cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for h mole cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.