Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Rare Diseases

Carcinoma, Renal Cell

Kidney Neoplasms

Urologic Neoplasms

Urogenital Neoplasms

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Kidney Diseases

Urologic Diseases

Male Urogenital Diseases

Renal Cell Carcinoma

Coagulants

All Drugs and Chemicals

Hemostatics

Robotic partial surgery

Jean-Christophe BERNHARD, PHU

The purpose of the study is to set up the larger prospective study on robotic partial nephrectomy, to describe the characteristics of patients operated for kidney cancer by this surgical procedure and also to determine the modalities of hemostasis in this procedure.

The primary objective of the study is to describe the characteristics of patients operated for kidney cancer by a robotic partial nephrectomy in France (recruiting centers, patient profile, tumor characteristics).

Secondary Objective(s):

1. To describe the surgical techniques and operative development.
2. To assess the modalities of haemostasis, during robotic partial nephrectomy.
3. To assess peri-operative morbidity in robotic partial nephrectomy and post-operative complications.
4. To assess the outcome of renal function after a robotic partial nephrectomy. This study is a national, multicenter, prospective, cohort.

RObotic PArtial Nephrectomy National Study

RObotic PArtial Nephrectomy National Study (RoPaN Study)

Necessity for nephrectomy or re-exploration

University Hospital, Bordeaux

Uterine Cervical Neoplasms

Uterine Cervical Dysplasia

Precancerous Conditions

Uterine Cervical Diseases

Uterine Diseases

Genital Diseases, Female

Genital Diseases

Uterine Neoplasms

Genital Neoplasms, Female

Cervical Intraepithelial Neoplasia

Pharmaceutical Solutions

Experimental Arm. Haemostasis at the end of the procedure using vaginal packing and Monsel's solution.

Haemostasis at the end of the procedure using only Monsel's solution.

This study will evaluate the role of vaginal packing after cervical conization as haemostasis technique

Vaginal Packing

Ricardo D Reis, MD

The LEEP conization is commonly used for cervical pathologies treatment. The techniques for hemostasis usually used are: cautery, Monsel's solution and vaginal pack. Actually, there is no consensus about the best technique and there is not much information that validates the use of some of that. To compare the use or not of vaginal pack as methods of hemostasis after LEEP conization for management of cervical lesions.

A randomized clinical trial was conducted at Gynecology Oncology Department/Barretos Cancer Hospital for patients with indication of LEEP conization. After local IRB approval, patients were allocated in two arms (50 patients each): without vaginal pack (group 1 - GP1) and with vaginal pack (group 2 - GP2). The Monsel's solution was used in all patients. Intraoperative and postoperative outcomes will be evaluated: operative time, intraoperative and postoperative bleeding, hormonal status, age, parity and cone specimens' characteristics as well as short-term outcome were recorded and compared using Chi-square test, Fisher exact test and t-test where appropriate.

Patients were allocated in two arms (50 patients each): without vaginal pack (group 1 - GP1) and with vaginal pack (group 2 - GP2).Randomization was generated through a computer program creating a random entry list in the study, separating in group 1 (local application of Monsel's solution without intra-vaginal gauze buffer) and group 2 (application of Monsel's solution with intra-vaginal gauze). In this way, all patients had an equal chance of being included in both groups.

The allocation of patients to one group or another was only known moments before the surgical procedure was started.

Comparing Two Techniques of Haemostasis After Cervical Conization

Randomized Clinical Trial Comparing Two Techniques of Haemostasis After Cervical Conization With High Frequency Surgery

Bleeding was assessed by the need for reintervention.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
RObotic PArtial Nephrectomy National Study	NCT03292549	Kidney Cancer	Robotic partial...	18 Years -	University Hospital, Bordeaux
Comparing Two Techniques of Haemostasis After Cervical Conization	NCT03293628	Cervical Intrae... Cervix Neoplasm	Vaginal Packing	19 Years - 68 Years	Barretos Cancer Hospital
RObotic PArtial Nephrectomy National Study	NCT03292549	Kidney Cancer	Robotic partial...	18 Years -	University Hospital, Bordeaux

Spots Global Cancer Trial Database for haemostasis

Every month we try and update this database with for haemostasis cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for haemostasis

Every month we try and update this database with for haemostasis cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for haemostasis cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.