Spots Global Cancer Trial Database for hedgehog pathway inhibitor
Every month we try and update this database with for hedgehog pathway inhibitor cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) As Maintenance Therapy in Patients With Ovarian Cancer in a Second or Third Complete Remission | NCT00739661 | Ovarian Cancer | Vismodegib 150 ... Placebo to vism... | 18 Years - | Genentech, Inc. | |
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma | NCT01878617 | Medulloblastoma | Craniospinal Ir... Cyclophosphamid... Cisplatin Vincristine Vismodegib Pemetrexed Gemcitabine Aerobic Trainin... Neurocognitive ... | 3 Years - 39 Years | St. Jude Children's Research Hospital | |
A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As First-Line Therapy for Metastatic Colorectal Cancer | NCT00636610 | Metastatic Colo... | Vismodegib 150 ... Placebo to vism... Bevacizumab Modified FOLFOX FOLFIRI | 18 Years - | Genentech, Inc. | |
A Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) in Patients With Advanced Basal Cell Carcinoma | NCT00833417 | Basal Cell Carc... | Vismodegib 150 ... | 18 Years - | Genentech, Inc. | |
A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study | NCT00959647 | Ovarian Cancer Basal Cell Carc... Metastatic Colo... | Vismodegib FOLFOX FOLFIRI Bevacizumab | 18 Years - | Genentech, Inc. | |
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma | NCT01878617 | Medulloblastoma | Craniospinal Ir... Cyclophosphamid... Cisplatin Vincristine Vismodegib Pemetrexed Gemcitabine Aerobic Trainin... Neurocognitive ... | 3 Years - 39 Years | St. Jude Children's Research Hospital | |
A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors | NCT01106508 | Advanced Solid ... Recurrent or Re... Locally Advance... | LEQ506 | 18 Years - | Novartis | |
Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS) | NCT01350115 | Basal Cell Carc... Gorlin Syndrome Nevoid Basal Ce... | LDE225 Placebo | 18 Years - | Novartis | |
A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As First-Line Therapy for Metastatic Colorectal Cancer | NCT00636610 | Metastatic Colo... | Vismodegib 150 ... Placebo to vism... Bevacizumab Modified FOLFOX FOLFIRI | 18 Years - | Genentech, Inc. |