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Spots is the easy way to track your skin, mole and cancer changes.

Spots Global Cancer Trial Database for hedgehog pathway inhibitor

Every month we try and update this database with for hedgehog pathway inhibitor cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) As Maintenance Therapy in Patients With Ovarian Cancer in a Second or Third Complete RemissionNCT00739661
Ovarian Cancer
Vismodegib 150 ...
Placebo to vism...
18 Years - Genentech, Inc.
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed MedulloblastomaNCT01878617
Medulloblastoma
Craniospinal Ir...
Cyclophosphamid...
Cisplatin
Vincristine
Vismodegib
Pemetrexed
Gemcitabine
Aerobic Trainin...
Neurocognitive ...
3 Years - 39 YearsSt. Jude Children's Research Hospital
A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As First-Line Therapy for Metastatic Colorectal CancerNCT00636610
Metastatic Colo...
Vismodegib 150 ...
Placebo to vism...
Bevacizumab
Modified FOLFOX
FOLFIRI
18 Years - Genentech, Inc.
A Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) in Patients With Advanced Basal Cell CarcinomaNCT00833417
Basal Cell Carc...
Vismodegib 150 ...
18 Years - Genentech, Inc.
A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer StudyNCT00959647
Ovarian Cancer
Basal Cell Carc...
Metastatic Colo...
Vismodegib
FOLFOX
FOLFIRI
Bevacizumab
18 Years - Genentech, Inc.
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed MedulloblastomaNCT01878617
Medulloblastoma
Craniospinal Ir...
Cyclophosphamid...
Cisplatin
Vincristine
Vismodegib
Pemetrexed
Gemcitabine
Aerobic Trainin...
Neurocognitive ...
3 Years - 39 YearsSt. Jude Children's Research Hospital
A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid TumorsNCT01106508
Advanced Solid ...
Recurrent or Re...
Locally Advance...
LEQ506
18 Years - Novartis
Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)NCT01350115
Basal Cell Carc...
Gorlin Syndrome
Nevoid Basal Ce...
LDE225
Placebo
18 Years - Novartis
A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As First-Line Therapy for Metastatic Colorectal CancerNCT00636610
Metastatic Colo...
Vismodegib 150 ...
Placebo to vism...
Bevacizumab
Modified FOLFOX
FOLFIRI
18 Years - Genentech, Inc.
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