Neoplasms

Blood and Lymph Conditions

All Conditions

Leukemia

Neoplasms by Histologic Type

Hematologic Diseases

Participants will be assigned an individual diet \& physical activity counselor through Healthways at Hopkins. This counselor will stay with the participant for the 24 months. The primary communication with the counselor will be via website \& email. Participants will be encouraged to consume a low-calorie, low-salt diet with 7-12 daily servings of fruits, vegetables \& low-fat dairy products. Calorie goals are based upon weight at study entry \& whether or not the weight loss goal has been met. Participants will gradually build to ≥ 180 minutes of moderate to vigorous physical activity per week, using the activity of their own choosing \& gradually adding bouts of ≥ 10 minutes in length. Monitoring \& Counselor Contacts: the first 3 months, the participants are encouraged to log into the web hub on a daily basis to record weight, food intake, \& physical activity. Participants who decline or drop out of the intervention program will remain on-study doing home visits \& questionnaires.

Participants will receive general information brochures on healthy living and weight loss but will not have access to the Healthways at Hopkins website or counselors.

Phone and web-based weight loss intervention (via Healthways at Hopkins counselor and website) focused on increasing physical activity and adhering to a healthy diet. Participants will log diet, physical activity, and weight in web-hub. Counselors will have access to this information to direct participants to goals and achievements.

individual diet & physical activity counselor and website through Healthways at Hopkins

Participants will be given information and links to CDC and American Cancer Society recommendations for healthy eating and physical activity.

self directed weight loss

Participants will complete behavioral questionnaires as well as diet and physical activity assessments through CCSS-based study website as baseline, 12 and 24 months.

questionnaires

During three time periods, at baseline and at 12 and 24 months.

fasting blood draw, measurement of height, weight and waist circumference, and blood pressure

Chaya Moskowitz, PhD

The EQUAL study has been designed for adult survivors of childhood acute lymphoblastic leukemia (ALL) who are overweight or obese. The purpose of this study is to see if diet and exercise can help people lose weight and improve other health problems. This two year study will compare two methods of informing participants about ways to lose weight.

Exercise and QUality Diet After Leukemia: The EQUAL Study

Weight loss will be evaluated in an intent-to-treat analysis with a linear mixed effects model with robust standard errors and an unstructured covariance matrix(50) using weight measured at each time points (0, 12 months and 24 months after randomization) as the outcome modeled as a function of time, randomization arm, a history of CRT, gender, age, and race together with interaction terms between time and randomization arm.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Exercise and QUality Diet After Leukemia: The EQUAL Study	NCT02244411	Adult Survivors...	individual diet... self directed w... questionnaires fasting blood d...	18 Years -	Memorial Sloan Kettering Cancer Center
Exercise and QUality Diet After Leukemia: The EQUAL Study	NCT02244411	Adult Survivors...	individual diet... self directed w... questionnaires fasting blood d...	18 Years -	Memorial Sloan Kettering Cancer Center

Spots Global Cancer Trial Database for individual diet & physical activity counselor and website through healthways at hopkins