Blood and Lymph Conditions

All Conditions

Anemia

Hematologic Diseases

Hematinics

All Drugs and Chemicals

Epoetin Alfa

Subcutaneous administration of epoetin beta 36,000 IU once-weekly for 12 weeks

epoetin beta

Subcutaneous administration of placebo once-weekly for 12 weeks

placebo

Yoshito Suzuki

This is a study to investigate the clinical efficacy and safety of epoetin beta 36,000 IU compared with placebo when administrated subcutaneously (s.c.) once-weekly for 12 weeks to anemic patients with lung cancer or gynecologic cancer undergoing chemotherapy.

Clinical Study of Epoetin Beta to Chemotherapy-Induced Anemia (CIA) Patients

A Phase Ⅲ Randomized Double-Blind Placebo-Controlled Study of Epoetin Beta for the Treatment of Chemotherapy-Induced Anemia (CIA) in Cancer Patients

Chugai Pharmaceutical

Chugai Pharmaceutical Co., Ltd.

Neoplasms

Skin and Connective Tissue Diseases

Symptoms and General Pathology

Wounds and Injuries

Breast Neoplasms

Hyperthermia

Fever

Breast Diseases

Skin Diseases

Immunostimulating Interstitial Laser Thermotherapy (imILT)

Immunostimulating Interstitial Laser Thermotherapy (imILT) is a specific form of thermotherapy, which, in addition to destroying tumor tissue, has been optimized to cause a tumor specific immunologic response.

Immunostimulating Interstitial Laser Thermotherapy

Kristjan S Asgeirsson, MD

Thermotherapy is a technology aiming at destroying tissue, for example tumor tissue. Immunostimulating Interstitial Laser Thermotherapy (imILT) is a specific form of thermotherapy, which, in addition to destroying tumor tissue, has been optimized to cause a tumor specific immunologic response. In laboratory animals the imILT method has also been shown to induce a so called abscopal effect. This means that when one tumor is treated with imILT other, untreated, tumors also decrease in size. The immunologic response has previously been characterized in breast cancer patients after receiving imILT treatment , and presumed abscopal effects induced by imILT have also been described in a malignant melanoma patient.

The purpose of this trial is to investigate the functionality and safety of the imILT treatment method in patients diagnosed with breast cancer.

The treatment method has successfully been used for treatment of patients with breast cancer and malignant melanoma. Treatment of breast cancer patients caused an increase of cytotoxic T lymphocytes in the treated tumor, as well as activated dendritic cells at the tumor border. Regulatory T lymphocytes decreased in the regional lymph nodes.

This trial is explorative, prospective, open and non-randomized. Five breast cancer patients will be treated in this trial, which is estimated to be carried out during a time period of 9 months.

Immunostimulating Interstitial Laser Thermotherapy in Breast Cancer

Interstitial Laser Thermotherapy (imILT) as a Treatment Option in Breast Cancer Patients Not Suitable for Surgical Excision

Evaluation by Response Evaluation Criteria in Solid Tumours (RECIST)

Evaluation of adverse events and laboratory analyses.

Analysis of instrument and user questionnaires relating to the ease of use.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Clinical Study of Epoetin Beta to Chemotherapy-Induced Anemia (CIA) Patients	NCT00628043	Anemia	epoetin beta placebo	20 Years - 79 Years	Chugai Pharmaceutical
Immunostimulating Interstitial Laser Thermotherapy in Breast Cancer	NCT03039127	Breast Neoplasm...	Immunostimulati...	-	Clinical Laserthermia Systems AB
Clinical Study of Epoetin Beta to Chemotherapy-Induced Anemia (CIA) Patients	NCT00628043	Anemia	epoetin beta placebo	20 Years - 79 Years	Chugai Pharmaceutical

Spots Global Cancer Trial Database for induced

Every month we try and update this database with for induced cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for induced

Every month we try and update this database with for induced cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for induced cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.