Neoplasms

All Conditions

Skin and Connective Tissue Diseases

Carcinoma

Breast Neoplasms

Carcinoma in Situ

Carcinoma, Ductal

Breast Carcinoma In Situ

Carcinoma, Intraductal, Noninfiltrating

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Breast Diseases

Skin Diseases

Adenocarcinoma

Patients just accept breast-conversing surgery without radiotherapy.

Boost with 20 Gy during BCS, EBRT with 46-50 Gy

Intraoperative Radiotherapy

Liao Ning, MD,PhD

Wen L Zhu

Whether the patients with low grade ductal carcinoma in situ breast cancer should accept radiationtherapy is uncertain.Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation during surgery followed by external-beam radiation to the entire breast may kill more tumor cells.The clinical trial is conducting to find out the effectiveness of radiation therapy during surgery in treating women who have undergone breast-conversing surgery for low grade ductal carcinoma in situ breast cancer.

Giving radiation during surgery followed by external-beam radiation to the entire breast may kill more tumor cells.The clinical trial is conducting to find out the effectiveness of radiation therapy during surgery in treating women who have undergone breast-conversing surgery for low grade ductal carcinoma in situ breast cancer.

Intra-operative Radiotherapy For Women With Ductal Carcinoma in Situ Breast Cancer

Intra-operative Radiotherapy After Breast-conversing Surgery in Treating Women With Ductal Carcinoma in Situ Breast Cancer

Within 5 years after surgery,we should evaluate ipsilateral breast tumor recurrence and Disease free survival as the most important outcome measure

Within 5 years after adjuvant chemotherapy,we should evaluateDisease free survival(DFS) rates as thet important outcome measure.

After surgery,we should evaluate overall survival (OR)rates as the secondary important outcome measure.

Liao Ning

Guangdong Academy of Medical Sciences

WRT:whole breast radiation after BCS with 46-50 Gy

whole breast radiation after BCS with 46-50 Gy

Whole breast radiation

Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation during surgery followed by external-beam radiation to the entire breast may kill more tumor cells.The clinical trial is conducting to compare the effectiveness of radiation therapy during surgery and whole-breast radiation therapy in treating women who have undergone breast-conversing surgery for Intermediate or high grade ductal carcinoma in situ breast cancer.

Comparison of Intra-operative Radiotherapy With Post-operative Radiotherapy for Women With Ductal Carcinoma in Situ

Comparison of the Efficacy of Intra-operative Radiation Therapy After Conserving Surgery With Post-operative Whole Breast Radiotherapy for Women With Ductal Carcinoma in Situ

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Intra-operative Radiotherapy For Women With Ductal Carcinoma in Situ Breast Cancer	NCT02389673	Breast Neoplasm...	Intraoperative ...	18 Years - 70 Years	Guangdong Academy of Medical Sciences
Comparison of Intra-operative Radiotherapy With Post-operative Radiotherapy for Women With Ductal Carcinoma in Situ	NCT02389699	Breast Neoplasm...	Intraoperative ... Whole breast ra...	18 Years - 70 Years	Guangdong Academy of Medical Sciences
Intra-operative Radiotherapy For Women With Ductal Carcinoma in Situ Breast Cancer	NCT02389673	Breast Neoplasm...	Intraoperative ...	18 Years - 70 Years	Guangdong Academy of Medical Sciences

Spots Global Cancer Trial Database for intermediate and high grade ductal carcinoma in situ （dcis）