Neoplasms

Digestive System Diseases

All Conditions

Rare Diseases

Colonic Neoplasms

Pneumoperitoneum

Peritoneal Diseases

Gastrointestinal Diseases

Oculocerebral Syndrome With Hypopigmentation

This is an international cohort (France and other international centers) which consists of including patients undergoing colorectal surgery performed at low pressure for benign or malignant pathology.This stage 2b cohort study is a pilot study assessing the best operative association with stable low-pressure pneumoperitoneum in order to optimize postoperative outcomes after mini invasive colorectal surgery.

Quentin QD DENOST, Prof

Hélène HMM MAILLOU-MARTINAUD

Nicolas NA AVELLANEDA

Ellen EV VAN EETVELDE

Ellen EVE VAN EETVELDE

Zaher ZL LAKKIS

Zaher ZL Lakkis

Quentin QD DENOST

Bertrand BT TRILLING

Antoine AB BROUQUET

Laura LBB BEYER-BERJOT

Panis YP Yves

Yves YP PANIS

Léon LM MAGGIORI

Jérémie JL Lefevre

Jérémie JL LEFEVRE

Gilles GM MANCEAU

Eddy EC COTTE

Jean-Jacques JJT TUECH

Markus MM MILLE

Antonino AS SPINELLI

Roel RH HOMPES

Patricia PT TEJEDOR

Frederic FR RIS

Deena DH HARJI

The objective of this prospective, international cohort is to incorporate the low stable pressure (using Airseal Insufflator) approach and its associated parameters into the early rehabilitation program after colorectal surgery so as to shorten hospitalization up to the ambulatory care and reduce postoperative pain and opioid consumption.

Laparoscopy is currently the gold standard for the vast majority of abdominal surgeries, and especially for colectomy for cancer or benign diseases. There are many data showing the benefits of the laparoscopic approach to colectomy in terms of morbidity, post-operative pain and analgesic consumption, length of hospital stay, cosmetic results, and improved patient satisfaction. In 2002, consensus European guidelines recommended insufflating at the lowest pressure that still provides sufficient exposure. Considering these results, low-pressure laparoscopy is one of the alternatives that have been developed to do away with the complications of the pneumoperitoneum while retaining its advantages.

However, other factors may influence the outcomes of the low-pressure pneumoperitoneum such as the use of humidification and warming gaz, robotic or microsurgical instrumentation, neuromuscular blockade, patient positioning, pre-stretching of the abdominal wall, ventilation-induced changes, and probably individual patient factors like obesity. These parameters could not be separately tested in randomized trial. We should consider all these parameters in a prospective international registry in order to optimize the benefit of low-pressure pneumoperitoneum in post-operative recovery.

Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY)

Low Stable Pressure Pneumoperitoneum in Colorectal Surgery : An Ideal Stage 2b Prospective International Cohort Study (CROSS STUDY)

There are no plans to share individual participant data (IPD) with other researchers

Evaluate the Length of hospital stay after colorectal surgery.

Pain is evaluated (Visual Analgesic Scale (Vas scores from 0 (no pain) to 10 (hurst worst))

Evaluate the impact on the opioid consumption after colorectal surgery;

Evaluate the impact of robotic, laparoscopic +/- microsurgical instrument, 3D laparoscopic vision surgery

Post operative Surgical and Medical morbidity according to the Clavien-Dindo Classification

Evaluate the impact of drugs, deep neuromuscular blockade, ventilation characteristics, intraoperative nociception monitoring, patient positioning, pre-stretching of the abdominal wall, and individual patient factors

Surgical and Medical morbidity at 30 days according to the Clavien-Dindo Classification

Spots Global Cancer Trial Database for length hospital stay