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patients in this group undergoing laparoscopic hepatectomy was performed with goal-directed LCVP based on hypovolemic phlebotomy (HP)

patients in this group undergoing laparoscopic hepatectomy was performed with LCVP but no hypovolemic phlebotomy (HP)

hypovolemic phlebotomy was performed after induction of anesthesia and before the star of parenchymal division, with a goal-directed low central venous pressure drop to 5mmHg.

hypovolemic phlebotomy

Shijiang Liu, MD

Yue Wang

Shijiang Liu

The goal of this clinical trial is to learn about goal-directed LCVP based on hypovolemic phlebotomy (HP) in laparoscopic hepatectomy. The main questions it aims to answer are:

1. The safety and feasibility of HP
2. To evaluate whether HP can reduce perioperative blood transfusion ratio Participants undergoing liver resection with HP was performed by the anesthesiologist. Blood was withdrawn approximately 30 min prior to the initiation of liver parenchymal transection from central venous. The aim was to maintain the CVP between 0 to 5 cmH2O. HP volume was 5-10 mL/kg of patient body weight, generally. Participants in control group undergoing liver resection without HP.

Goal-directed LCVP Based on HP in Laparoscopic Hepatectomy

The Application of Goal-directed Low Central Venous Pressure Based on Hypovolemic Phlebotomy in Laparoscopic Hepatectomy

The primary end point of the study was the proportion of patients who required transfusion of allogeneic red blood cell products during laparoscopic hepatectomy or at any time during the hospitalization during the index admission.

how many patients have the pringle maneuver

The First Affiliated Hospital with Nanjing Medical University

Clinical Professor

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Goal-directed LCVP Based on HP in Laparoscopic Hepatectomy	NCT05887661	Hepatocellular ...	hypovolemic phl...	18 Years -	The First Affiliated Hospital with Nanjing Medical University
Goal-directed LCVP Based on HP in Laparoscopic Hepatectomy	NCT05887661	Hepatocellular ...	hypovolemic phl...	18 Years -	The First Affiliated Hospital with Nanjing Medical University

Spots Global Cancer Trial Database for low central venous pressure