Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

Group A (35 patients) have standard curative conservative breast surgery without integration of plastic techniques .

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Group B(35 patients) have curative oncoplastic surgery in which plastic techniques integrated with oncological procedures

Standard conservative breast surgery

Oncoplastic breast surgery

This non randomized study is a comparative study between standard conservative breast surgery and oncoplastic surgery as regard margin status and patient satisfaction.

This planned study was conducted on 70 female patients presented to our tertiary referral breast unit at Ain Shams University hospitals with breast cancer amid the period from September 2012 to May 2013 .

Every one of them signed an informed consent to partake in this study that was approved in a meeting held by the ethical committee on august 2012 at Ain Shams University. All patients sharing in the study received closed envelope before surgery in a randomized way in which the surgical technique is written either standard conservative surgery or oncoplastic surgery(Double Blind).

Our patients were partitioned into 2 equal groups: group A (35patients) who underwent standard conservative surgery, group B (35patients) who underwent oncoplastic surgery.

A Comparative Study Between Oncoplastic Breast Surgery and Standard Conservative Surgery:Margin Status and Patient Satisfaction

A Comparative Study Between Oncoplastic Breast Surgery and Standard Conservative Surgery:Margin Status and Patient Satisfaction Among Egyptian Females

Ain Shams University

Lecturer of General surgery

Digestive System Diseases

Gland and Hormone Related Diseases

Rare Diseases

Pancreatic Neoplasms

Cholangiocarcinoma

Adenocarcinoma

Carcinoma

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Pancreatic Cancer

Bile Duct Cancer

"Conventional" method of pathological evaluation

LEEPP includes: 1) multicolor inking; 2) axial slicing; 3) circumferential margin; 4) 1-mm clearance

Leeds Pathology Protocol (LEEPP)

This multicentric prospective randomized controlled trial (RCT) compares the Leeds Pathology Protocol (LEEPP) with other "conventional" pathological protocol of PD specimen for periampullary cancer. Our aims were to evaluate the impact of the protocol and of the clearance on R1 rate and its prognostic value.

Margin Status After Pancreaticoduodenectomy for Cancer

Margin Status After Pancreaticoduodenectomy for Cancer. Results of a Multicentric Prospective Randomized Trial

To evaluate difference in terms of R1 resection rates between study groups with 0-mm and 1-mm clearance

To evaluate differences in pathological results (T status, N status, number of blocks, number of lymphnodes, etc) between the two study groups

To evaluate the correlation between R1 resection and oncological results (local recurrence, overall survival) in the two study groups

Humanitas Hospital, Italy

Azienda Ospedaliero, Universitaria Pisana

Medical University of Silesia

Campus Bio-Medico University

M.D.

Breast Carcinoma In Situ

Carcinoma in Situ

radio-labelled (I-125) titanium seed inserted via needle into nonpalpable breast lesion and gamma probe used to guide surgery

radioguided seed localization for nonpalpable breast cancers

Peter J Lovrics, MD

Mary Townsend

The purpose of this study is to determine whether a new surgical technique (radioguided seed localization) for localizing nonpalpable breast tumours is better than the standard technique (needle localization).

Most breast cancers are removed by partial mastectomy/lumpectomy. The most important factor in ensuring that the cancer does not return in the breast is to ensure that it is completely removed during surgery. Complete removal is dependent on having a rim of normal tissue (clear margin) surrounding the cancer. If the margin is positive, or the cancer recurs, more surgery or mastectomy is required. Approximately one third of breast cancers are detected by mammograms or ultrasounds and cannot be felt by patients or physicians. Accordingly, a localization technique is required to help the surgeon to find and remove the cancer. The current technique (needle localization) has a higher chance of having cancer cells at the margin. This is a study about a surgical technique. The objective of this comparison study is to determine whether a new technique (radioguided seed localization) is a better way to remove nonpalpable breast cancers. The main objective of this study is to determine if the new technique generates fewer positive margins compared to the standard technique. An improved technique would benefit thousands of women every year.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
A Comparative Study Between Oncoplastic Breast Surgery and Standard Conservative Surgery:Margin Status and Patient Satisfaction	NCT03012152	Breastcancer	Standard conser... Oncoplastic bre...	- 60 Years	Ain Shams University
Margin Status After Pancreaticoduodenectomy for Cancer	NCT03267966	Pancreatic Canc... Cholangiocarcin... Ampullary Cance...	Leeds Pathology...	18 Years -	Campus Bio-Medico University
Trial Comparing Radioactive Seed Localization to Standard Procedure for Non-palpable Breast Cancers	NCT00225927	Breast Cancer I... Stage 0 Breast ...	radioguided see...	18 Years -	McMaster University

Spots Global Cancer Trial Database for margin status