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Neoplasms, Glandular and Epithelial

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Nasopharyngeal Neoplasms

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routine oral care and functional exercise.

Massage of Maxillofacial and oral cavity plus routine oral care and functional exercise

Massage of Maxillofacial and Oral Cavity is performed five times a day, each part lasts 1-2 minutes, repeating 3 cycles. The maxillofacial and oral massage last from the first day of radiotherapy to three months after last radiotherapy.

Massage of Maxillofacial and Oral Cavity

A total of 160 cases of nasopharyngeal carcinoma patients who met the inclusion criteria were randomly assigned to two groups. The experimental group was given massage of maxillofacial and oral cavity plus routine oral care and functional exercise. The control group was given routine oral care and functional exercise. Analyze the difference of incidence of severe acute radioactive oral mucositis in these two groups.

160 nasopharyngeal carcinoma patients were enrolled and randomly assigned to two groups in a 1:1 ratio. The experimental group was given massage of maxillofacial and oral cavity plus routine oral care and functional exercise, the control group was only given routine oral care and functional exercise. Assess the condition of oral mucosa, according to the grading standard of RTOG acute radiation injury, everyday during radiotherapy. After radiotherapy, follow up the condition of oral mucosa one time per month for a total three times. Then analyze the incidence difference between two groups.

massage method：The duration of the massage lasts from the first day of radiotherapy to three months after the end of radiotherapy，5 times a day（After getting up, before breakfast, lunch, dinner and going to bed). massage of maxillofacial includes the left and right cheeks, the upper jaw, the lower jaw, and around the mouth. Oral Massage includes the tongue, hard palate, the gums, and the bucca. Each part lasts 1-2min，repeating 3 cycles each time. Patients who could finished at least 75% are included in the statistical analysis.

Using Massage of Maxillofacial and Oral Cavity to Prevent Radioactive Oral Mucositis

Randomized, Controlled Clinical Study of Using Massage of Maxillofacial and Oral Cavity to Prevent Oral Mucositis in Patients With Nasopharyngeal Carcinoma Undergoing Radiotherapy

the status of oral mucosa was evaluated daily during radiotherapy. According to the grading standard of RTOG acute radiation injury, statistical analysis was made on whether there was a difference and statistical significance in the incidence rate of oral mucositis with radiation above grade 3 between the two groups.

the time at which the radioactive oral mucosa occurred; Difficulty in opening your mouth.

Xinqiao Hospital of Chongqing

Professor

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Using Massage of Maxillofacial and Oral Cavity to Prevent Radioactive Oral Mucositis	NCT03788499	Nasopharyngeal ...	Massage of Maxi...	18 Years - 70 Years	Xinqiao Hospital of Chongqing
Using Massage of Maxillofacial and Oral Cavity to Prevent Radioactive Oral Mucositis	NCT03788499	Nasopharyngeal ...	Massage of Maxi...	18 Years - 70 Years	Xinqiao Hospital of Chongqing

Spots Global Cancer Trial Database for maxillofacial and oral cavity