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Acetic Acid

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Xiaobo Li, MD. Ph.D

Chromoendoscopy (indigo carmine or acetic acid) and Narrow Band Imaging (NBI) could make accurate evaluation in predicting of invasive depth of colorectal neoplasia. NBI could be the first choice.

To compare the diagnostic accuracy of chromoendoscopy indigo carmine or acetic acid and NBI for differentiating neoplastic from non-neoplastic colorectal lesions, differentiating adenomas from carcinomas, and differentiating early carcinomas from invasive ones.

Included colorectal lesions consecutively distribute in a 1:1 ratio to 2 groups.

All the lesions will be removed endoscopically or surgically and examine histologically by an independent gastrointestinal pathologist.

Histological diagnosis is determined according to the World Health Organization (WHO) criteria. Pedunculated lesions are categorized according to Haggitt's classification.

Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions

Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions Using Magnifying Colonoscopy With Narrow Band Imaging, Indigo Carmine, and Acetic Acid Staining

Shanghai Jiao Tong University School of Medicine

Shanghai Institute of Digestive Disease，Renji Hospital, Shanghai Jiao Tong University School of Medicine

Magnification narrow band imaging (NBI) can make accurate evaluation in in predicting of invasive depth of colorectal neoplasia.

NBI could be used in stratifying patients for endoscopic resection or surgery and got an accurate evaluation.

All the lesions will be removed endoscopically or surgically and examined histologically by an independent gastrointestinal pathologist.

Histological diagnosis is determined according to the World Health Organization (WHO) criteria.Pedunculated lesions are categorized according to Haggitt's classification.

The Value of Narrow Band Imaging in Stratifying Patients for Endoscopic Resection or Surgery

The Value of NBI in Stratifying Patients for Endoscopic Resection or Surgery

Study title	NCT ID	Conditions	Eligibility	Organization
Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions	NCT01521091	Colorectal Neop...	18 Years - 90 Years	Shanghai Jiao Tong University School of Medicine
The Value of Narrow Band Imaging in Stratifying Patients for Endoscopic Resection or Surgery	NCT01521104	Colorectal Neop...	18 Years - 90 Years	Shanghai Jiao Tong University School of Medicine
The Value of Narrow Band Imaging in Stratifying Patients for Endoscopic Resection or Surgery	NCT01521104	Colorectal Neop...	18 Years - 90 Years	Shanghai Jiao Tong University School of Medicine
The Value of Narrow Band Imaging in Stratifying Patients for Endoscopic Resection or Surgery	NCT01521104	Colorectal Neop...	18 Years - 90 Years	Shanghai Jiao Tong University School of Medicine
The Value of Narrow Band Imaging in Stratifying Patients for Endoscopic Resection or Surgery	NCT01521104	Colorectal Neop...	18 Years - 90 Years	Shanghai Jiao Tong University School of Medicine

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