Neoplasms

Digestive System Diseases

Gland and Hormone Related Diseases

All Conditions

Rare Diseases

Pancreatic Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Endocrine Gland Neoplasms

Gastrointestinal Diseases

Pancreatic Diseases

Endocrine System Diseases

Pancreatic Cancer

Endoscopic ultrasound-guided fine needle aspiration using a stylet slow-pull technique of solid pancreatic mass

Endoscopic ultrasound-guided fine needle aspiration using negative pressure technique of solid pancreatic mass

pancreatic solid mass punctured with a 22G endoscopic ultrasound needle

Endoscopic ultrasound-guided fine needle aspiration

Spencer Cheng

50 patients with pancreatic mass will undergo endoscopic ultrasound-guided fine needle aspiration using two techniques: negative pressure and slow-pull. Cytological results will be compared.

The study will analyze the cytological results of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) of pancreatic mass using two different techniques of needle suction. Negative pressure and slow-pull. 50 patients with pancreatic mass will be submitted to four passes with both techniques. Each patient will be randomized to decide which technique will be first and subsequently on a alternated fashion until four passes are completed. Smear cytology and cell block preparations for each technique were obtained. The pathologist was blinded for the EUS-FNA technique.

EUS-FNA of Solid Pancreatic Mass: Comparison Between Negative Pressure and Slow-pull Technique

Endoscopic Ultrasound-guided Fine Needle Aspiration (EUS-FNA) of Solid Pancreatic Mass: Comparison Between Negative Pressure and Slow-pull Technique

cytological results after endoscopic ultrasound fine needle aspiration

Boston Scientific Corporation

Medi - Globe

University of Sao Paulo General Hospital

Infections

Symptoms and General Pathology

Wounds and Injuries

Communicable Diseases

Sarcoma

Wound Infection

Neoplasms, Connective and Soft Tissue

Neoplasms by Histologic Type

Soft Tissue Sarcoma

120 hours of negative pressure wound therapy (ActiVAC, KCI) applied to a primarily closed ('acute') wound.

Absorbant dressings applied in a standard fashion, i.e. only changed as necessary

Negative Pressure Wound Therapy (ActivVAC, KCI)

Current absorbent dressing is 'tegaderm with absorbent pad' (3M)

Standard dressings

Sanjay Gupta, MBBS

This randomised controlled trial aims to evaluate the difference in surgical site infection following excision of soft tissue sarcomas. The intervention is a negative wound pressure therapy dressing for 120 hours, the control is standard absorbent dressings

Hypothesis: The application of a negative pressure wound therapy (NPWT) dressing will reduce rates of wound breakdown in patients with resection of soft tissue sarcomas which are primarily closed.

Patients will be randomised into either NPWT or standard absorbent dressings with primary outcome measure of surgical site infection according to the Health Protection Agency guidance. Secondary outcomes are; time to wound dryness, delayed discharge from hospital, adverse events, cost estimation

Negative Pressure Dressing Therapy in Soft Tissue Sarcoma Surgery

Negative Pressure Dressings Versus Non-negative Pressure Dressing for Wound Care Following Soft Tissue Sarcoma Excision

As diagnosed by independent observer according to the Healthcare Protection Agency (UK) guidelines

Time to the nearest 12 hour period by which there is no further wound exudate (e.g. staining on dressing)

Number of additional hospital stays attributable to wound issues

Cost analysis to evaluate potential offset of costs for NPWT

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
EUS-FNA of Solid Pancreatic Mass: Comparison Between Negative Pressure and Slow-pull Technique	NCT03111368	Pancreatic Neop...	Endoscopic ultr...	18 Years -	University of Sao Paulo General Hospital
EUS-FNA of Solid Pancreatic Mass: Comparison Between Negative Pressure and Slow-pull Technique	NCT03111368	Pancreatic Neop...	Endoscopic ultr...	18 Years -	University of Sao Paulo General Hospital
Negative Pressure Dressing Therapy in Soft Tissue Sarcoma Surgery	NCT02901405	Sarcoma Wound Infection	Negative Pressu... Standard dressi...	16 Years -	NHS Greater Glasgow and Clyde

Spots Global Cancer Trial Database for negative pressure