Neoplasms

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Urologic Neoplasms

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Neoplasms, Glandular and Epithelial

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Urogenital Diseases

Female Urogenital Diseases

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Female Urogenital Diseases and Pregnancy Complications

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Male Urogenital Diseases

Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma

39 patients with high complexity renal tumors who underwent laparoscopic partial nephrectomy

39 patients with high complexity renal tumors who underwent laparoscopic radical nephrectomy

Nephron sparing minimally invasive surgery

laparoscopic partial nephrectomy

Completely removal of kidney by using laparoscopic surgery

Laparoscopic radical nephrectomy

Ender Ozden, Prof.

Saban Sarıkaya, Prof.

Mehmet Mercimek, MD, FEBU

Yakup Bostancı, Prof.

Murat Gulsen, MD

The study aims to investigate the rationale for LPN in patients with high-complexity renal tumors in terms of oncologic and functional outcomes.

From November 2009 to October 2018, 399 patients underwent LPN and 307 patients to laparoscopic radical nephrectomy (LRN). 41 patients with RENAL score ≥ 10 enrolled in LPN and 265 patients to the LRN group. Propensity score matching (matched by age, gender, clinical tumor stage, tumor size, baseline renal function, comorbidities such as diabetes mellitus (DM), hypertension (HT), coronary artery disease (CAD), and final tumor pathology of RCC) was used to reduce selection bias. Functional and oncological outcomes were compared between the two groups. After propensity score analysis, 39 patients in the LRN group were matched with 39 in the LPN group.

LPN in Patients With High-complex Renal Tumors

Comparison of Laparoscopic Partial Nephrectomy Versus Laparoscopic Radical Nephrectomy in Patients With High-Complexity Renal Tumors: A Propensity Score Matched Analysis

The clamp time of the renal artery and vein which is required to complete tumor excision and renorrhaphy

abnormal problmes that may be seen after surgery and require additional intervention, treatment or follow-up

serum creatinine level (mg /dL) and estimated glomerular filtration rate (CKD Epidemiology Collaboration (CKD-EPI) equation) (mL/min/1.73 m2)

presence or absence of tumors at the surgical margin

evaluation of preoperative and postoperative renal functions according to chronic kidney disease stages

Presence or absence of local and/or distal tumor recurrence

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
LPN in Patients With High-complex Renal Tumors	NCT04933604	Renal Cancer Renal Neoplasm Renal Cell Carc... Surgery Oncology Kidney Ischemia Kidney Injury Urologic Neopla... Urologic Cancer Kidney Neoplasm...	laparoscopic pa... Laparoscopic ra...	18 Years - 80 Years	Samsun Liv Hospital
LPN in Patients With High-complex Renal Tumors	NCT04933604	Renal Cancer Renal Neoplasm Renal Cell Carc... Surgery Oncology Kidney Ischemia Kidney Injury Urologic Neopla... Urologic Cancer Kidney Neoplasm...	laparoscopic pa... Laparoscopic ra...	18 Years - 80 Years	Samsun Liv Hospital
LPN in Patients With High-complex Renal Tumors	NCT04933604	Renal Cancer Renal Neoplasm Renal Cell Carc... Surgery Oncology Kidney Ischemia Kidney Injury Urologic Neopla... Urologic Cancer Kidney Neoplasm...	laparoscopic pa... Laparoscopic ra...	18 Years - 80 Years	Samsun Liv Hospital
LPN in Patients With High-complex Renal Tumors	NCT04933604	Renal Cancer Renal Neoplasm Renal Cell Carc... Surgery Oncology Kidney Ischemia Kidney Injury Urologic Neopla... Urologic Cancer Kidney Neoplasm...	laparoscopic pa... Laparoscopic ra...	18 Years - 80 Years	Samsun Liv Hospital

Spots Global Cancer Trial Database for nephrometry score