Neoplasms

Gland and Hormone Related Diseases

All Conditions

Rare Diseases

Adrenocortical Adenoma

Adrenal Gland Neoplasms

Adenoma

Adrenal Cortex Neoplasms

Endocrine Gland Neoplasms

Adrenal Cortex Diseases

Adrenal Gland Diseases

Endocrine System Diseases

Adenoma of the Adrenal Gland

Vasoconstrictor Agents

Respiratory System Agents

All Drugs and Chemicals

Herbal and Botanical

Epinephrine

Racepinephrine

Epinephryl borate

Mace

Nutmeg

CT imaging

Mojca Jensterle, MD, PhD

The data on long term natural history of benign nonfunctioning adrenal tumors (NFATs) are lacking. The aim is to identify clinical characteristics associated with tumor growth and progression to mild autonomous cortisol excess over time.

After being informed about the study, all patients with NFAT given written informed consent will underwent a control visit approximatly 10 years after initial visit at the outpateint clinic at the Department of Endocrinology, Diabetes and Metabolic Disease, University Medical Center Ljubljana, Ljubljana, Slovenia. The included patients will be divided in three groups regarding the BMI as follows: BMI \< 25 kg/m2, 25-30 kg/m2 and \> 30 kg/m2. The investigators will assess clinical, and laboratory parameters and CT findings at the follow up visit and compere them to baseline characteristics.

Natural History of NFAI: 10 Year Follow-up Results

Natural History of Benign Nonfunctioning Adrenal Tumors: 10 Year Follow-up Results

To determine if and in how many pateints NFAI progressed to MACE.

NFAI: when cortisol after 1 mg overnight dexamethasone (ODST) suppression test is \< 50 nmol/l and no typical clinical signs of Cushing's syndrome are present. Pheochromocytoma and primary aldosteronism will be excluded.

MACE: when cortisol after 1 mg overnight dexamethasone (ODST) suppression test is \> 50 nmol/l.

To determine the change in size of NFAI on the CT scan (mm).

To determine the change in BMI and its correlation with outcome 1 and 2.

Weight and height will be combined to report BMI in kg/m\^2.

University of Ljubljana, Faculty of Medicine

University Rehabilitation Institute, Republic of Slovenia

University Medical Centre Ljubljana

Clinical Professor

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Natural History of NFAI: 10 Year Follow-up Results	NCT04616703	Adrenal Inciden...	CT imaging	18 Years -	University Medical Centre Ljubljana
Natural History of NFAI: 10 Year Follow-up Results	NCT04616703	Adrenal Inciden...	CT imaging	18 Years -	University Medical Centre Ljubljana

Spots Global Cancer Trial Database for nfai

Every month we try and update this database with for nfai cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for nfai

Every month we try and update this database with for nfai cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for nfai cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.