Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Rare Diseases

Melanoma

Skin Neoplasms

Neuroendocrine Tumors

Neuroectodermal Tumors

Neuroectodermal Tumors, Primitive

Neoplasms, Germ Cell and Embryonal

Neoplasms by Histologic Type

Neoplasms, Nerve Tissue

Nevus, Pigmented

Nevus

Nevi and Melanomas

Skin Diseases

Neuroendocrine Tumor

Neuroepithelioma

Anti-Infective Agents

Central Nervous System Depressants

All Drugs and Chemicals

Ethanol

Patients seen in the dermatology clinic with suspicious skin lesion to be biopsied will have 4 skin swabs, 2 of the skin lesion and 2 of an area of unafflicted skin.

Cleanse an area of unafflicted (control) skin with a cotton 2 x 2 dampened with saline.

Dermatology patients

Cleanse a suspicious lesion (potential melanoma) with a saline cotton swab.

This intervention follows the standard of care for patients with a suspicious skin lesion (potential melanoma) the physician plans to biopsy. The alcohol swab used to prep the site will be stored for testing rather than discarded.

Cleanse an area of unafflicted (control) skin with an alcohol swab.

Nikolaus Gravenstein, MD

The purpose of this research study is to determine if a very sensitive chemistry lab analyzer can be used to smell a skin cancer (like melanoma) similar to some dogs.

Types of skin cancer, like melanoma, are likely to spread and are becoming increasingly common. At this time, healthcare providers look at patient's skin and remove a sample of suspicious areas of the skin (biopsy) to test for cancer.

This research study will inspect cotton and cloth swabs of normal skin and suspicious areas of the skin that are going to be biopsied just before the biopsy. The swabs will be looked at with a very sensitive chemistry lab analyzer to see if the lab analyzer can confirm conventional lab test findings.

Analysis of Skin Lesions for Melanoma Presence by Volatile Spectroscopy Techniques

Determine if the melanomas have unique identifying spectra that might be applied to noninvasive melanoma skin cancer screening in lieu of taking a biopsy

University of Florida

Leiomyoma

Myofibroma

Neoplasms, Connective and Soft Tissue

Neoplasms, Connective Tissue

Connective Tissue Diseases

This is an FDA approved noninvasive treatment for fibroids that uses highly focused ultrasound waves to damage fibroid tissue.

MR Guided Focused Ultrasound

This is a placebo treatment that requires a participant to undergo identical procedures as those of the actual MR Guided Focused Ultrasound procedure, but higly focused ultrasound waves are not directed at the uterine fibroid.

Placebo MR Guided Focused Ultrasound

Vanessa Jacoby, MD

This is a pilot randomized, blinded, placebo-controlled trial of a noninvasive, FDA approved treatment for uterine fibroids called MR Guided Focused Ultrasound (MRgFUS). Our hypothesis is that MRgFUS provides superior relief of fibroid symptoms compared with the placebo, a sham MRgFUS treatment. The investigators will recruit 20 premenopausal women with symptomatic uterine fibroids to participate in the trial. Participants will be randomly assigned in a 2:1 ratio to the active treatment arm (MRgFUS) versus the sham MRgFUS treatment. Participants will remain blinded to their group assignment for 3 months. After 3 months, participants will be told their treatment group and those assigned to the sham group will be offered complimentary MRgFUS if they desire it. Women will be excluded if they are inappropriate candidates for a 3 month delay in fibroid treatment, such as those with significant anemia. The investigators will assess the change from baseline to 1 and 3 months after treatment in fibroid symptoms, quality of life, fibroid volume measured by MRI, and hematocrit.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Analysis of Skin Lesions for Melanoma Presence by Volatile Spectroscopy Techniques	NCT02393001	Melanoma	Dermatology pat... Dermatology pat... Dermatology pat... Dermatology pat...	18 Years -	University of Florida
Magnetic Resonance Guided Focused Ultrasound for Uterine Fibroids	NCT01377519	Uterine Fibroid...	MR Guided Focus... Placebo MR Guid...	18 Years - 99 Years	University of California, San Francisco
Analysis of Skin Lesions for Melanoma Presence by Volatile Spectroscopy Techniques	NCT02393001	Melanoma	Dermatology pat... Dermatology pat... Dermatology pat... Dermatology pat...	18 Years -	University of Florida
Analysis of Skin Lesions for Melanoma Presence by Volatile Spectroscopy Techniques	NCT02393001	Melanoma	Dermatology pat... Dermatology pat... Dermatology pat... Dermatology pat...	18 Years -	University of Florida
Magnetic Resonance Guided Focused Ultrasound for Uterine Fibroids	NCT01377519	Uterine Fibroid...	MR Guided Focus... Placebo MR Guid...	18 Years - 99 Years	University of California, San Francisco
Analysis of Skin Lesions for Melanoma Presence by Volatile Spectroscopy Techniques	NCT02393001	Melanoma	Dermatology pat... Dermatology pat... Dermatology pat... Dermatology pat...	18 Years -	University of Florida

Spots Global Cancer Trial Database for noninvasive

Every month we try and update this database with for noninvasive cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for noninvasive

Every month we try and update this database with for noninvasive cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for noninvasive cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.