Spots Global Cancer Trial Database for p53
Every month we try and update this database with for p53 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| A Study of Aezea® (Cenersen) in Transfusion Dependent Anemia Associated With Myelodysplastic Syndrome (MDS) | NCT02243124 | Myelodysplastic... | cenersen Dexamethasone | 18 Years - 95 Years | Eleos, Inc. | |
| A Study of Siremadlin in Combination With Venetoclax Plus Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Chemotherapy. | NCT05155709 | Acute Myeloid L... | siremadlin venetoclax azacitidine | 18 Years - 99 Years | Novartis | |
| A Safety, Pharmacokinetic and Pharmacodynamic Study of Kevetrin in Patients With Advanced Solid Tumors | NCT01664000 | Solid Tumors | thioureidobutyr... | 18 Years - | Cellceutix Corporation | |
| Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer | NCT03358017 | Triple Negative... | Zoledronate Atorvastatin 80... Standard neoadj... | 18 Years - | Mario Negri Institute for Pharmacological Research | |
| Safety and Efficacy Study of ALT-801 to Treat Progressive Metastatic Malignancies | NCT00496860 | Progressive Met... | ALT-801 | 18 Years - | Altor BioScience | |
| Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutations | NCT04906031 | Myelodysplastic... Acute Myeloid L... Myeloid Maligna... Temperature-Sen... Sodium Stiboglu... P53 Mutation | Sodium stiboglu... | 18 Years - 75 Years | First Affiliated Hospital of Jinan University | |
| Zanubrutinib Combined With R-CHOP in the Treatment of Newly Diagnosed DLBCL With p53 Protein Expression | NCT06005870 | Diffuse Large B... | Zanubrutinib pl... | 18 Years - 75 Years | Huazhong University of Science and Technology | |
| A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies | NCT03560882 | Malignant Disea... Solid Tumor Acute Myeloid L... Myelodysplastic... Cancer Relapsed Hemato... | Atorvastatin | 18 Years - | University of Kansas Medical Center | |
| Curcumin Supplementation in Cervical Cancer | NCT06080841 | Locally Advance... | Curcumin Curcumin + Pipe... | 18 Years - | National Institute of Cancerología | |
| Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy | NCT00001440 | Breast Neoplasm Neoplasm Metast... | Autologous T ce... Interleukin-2 | - | National Institutes of Health Clinical Center (CC) | |
| Unusual Infiltrative Patterns of Malignant Cells in Endometrial Carcinoma and Immunohistochemical Expression of P53 | NCT05755893 | Endometrial Can... | 20 Years - 80 Years | Assiut University | ||
| QUILT-2.008: Study of ALT-801 With Cisplatin in Patients With Metastatic Melanoma | NCT01029873 | Metastatic Mela... | Cisplatin ALT-801 | 18 Years - | Altor BioScience | |
| Ruxolitinib in the Treatment of Chronic Lymphocytic Leukemia | NCT02015208 | Chronic Lymphoc... | Ruxolitinib | 65 Years - | Sunnybrook Health Sciences Centre | |
| Unusual Infiltrative Patterns of Malignant Cells in Endometrial Carcinoma and Immunohistochemical Expression of P53 | NCT05755893 | Endometrial Can... | 20 Years - 80 Years | Assiut University | ||
| Study With Wee-1 Inhibitor AZD1775 (MK-1775) and Carboplatin to Treat p53 Mutated Refractory and Resistant Ovarian Cancer | NCT01164995 | Epithelial Ovar... | MK-1775 and car... | 18 Years - | The Netherlands Cancer Institute | |
| Study With Wee-1 Inhibitor AZD1775 (MK-1775) and Carboplatin to Treat p53 Mutated Refractory and Resistant Ovarian Cancer | NCT01164995 | Epithelial Ovar... | MK-1775 and car... | 18 Years - | The Netherlands Cancer Institute | |
| Zanubrutinib Combined With R-CHOP in the Treatment of Newly Diagnosed DLBCL With p53 Protein Expression | NCT06005870 | Diffuse Large B... | Zanubrutinib pl... | 18 Years - 75 Years | Huazhong University of Science and Technology | |
| EDICT - Exercise inDuced Changes In Colorectal Cancer Tissues | NCT02056691 | Colorectal Canc... | Exercise progra... Muscle biopsy | 18 Years - | The Royal Bournemouth Hospital | |
| P16 Staining as Prognostic Biomarker in Serous Papillary Endometrial Cancer | NCT01267357 | Serous Papillar... | no intervention | 18 Years - | Rambam Health Care Campus | |
| Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy | NCT00001440 | Breast Neoplasm Neoplasm Metast... | Autologous T ce... Interleukin-2 | - | National Institutes of Health Clinical Center (CC) | |
| Ruxolitinib in the Treatment of Chronic Lymphocytic Leukemia | NCT02015208 | Chronic Lymphoc... | Ruxolitinib | 65 Years - | Sunnybrook Health Sciences Centre | |
| Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features | NCT05255653 | Endometrial Can... | Olaparib Pelvic external... Chemotherapy Durvalumab Medroxyprogeste... Megestrol Aceta... Vaginal brachyt... Observation | 18 Years - | Leiden University Medical Center | |
| P53 Gene Combined With Radio- and Chemo-therapy in Treatment of Unresectable Locally Advanced Head and Neck Cancer | NCT02429037 | Advanced Head a... | rAd-p53 radiation Cisplatin | 18 Years - | Shenzhen SiBiono GeneTech Co.,Ltd |
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