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Using the 22G ProCore needle for sampling pancreatic mass lesions, the tissue obtained will be compared to the standard FNA needle.

Using the 22G standard fine needle aspiration needle (FNA) for sampling pancreatic mass lesions, the tissue obtained will be compared to the 22 G ProCore needle.

Tissue will be acquired with the 22G Procore biopsy needle and the sample will be compared to the sample obtained with the 22G standard FNA needle.

22G ProCore biopsy needle

Tissue will be acquired with the 22G standard FNA biopsy needle and the sample will be compared to the sample obtained with the 22G ProCore biopsy needle.

22G standard FNA needle

Shyam Varadarajulu, MD

The aim of this research study is to identify the best needle for performing biopsy during EUS procedures. There are two types of needles for performing biopsy: A FNA needle that provides a small sample of tissue for analysis and a 22G ProCore needle that provides larger amount of tissue. It is not clear at this point which of the two needles is superior for performing biopsy. This study will attempt to identify the better needle by assessing the performance of both needles in a randomized fashion.

In this randomized trial, the 22G standard fine needle aspiration needle was compared with the newly developed 22G ProCore needle for sampling pancreatic mass lesions during endoscopic ultrasound. Patients were randomized into the two needle groups and then various outcomes were compared between the two needle types, including the number of passes needed to establish a diagnosis, the ability to procure enough tissue sample to be able to make a diagnosis, the rates of needle failure and complication rates.

22G FNA Needle vs. 22G ProCore Needle

Randomized Trial Comparing the 22-gauge Aspiration and 22-gauge Biopsy Needles for EUS-guided Sampling of Solid Pancreatic Mass Lesions

Malfunction of the needle during endoscopic ultrasound-guided sampling of the pancreatic mass lesion before a diagnosis is achieved

AdventHealth

Acquire biopsy with procore needle

Procore Biopsy: Acquire tissue with procore biopsy needle

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
22G FNA Needle vs. 22G ProCore Needle	NCT01394159	Pancreatic Neop...	22G ProCore bio... 22G standard FN...	19 Years -	AdventHealth
22G FNA Needle vs. 22G ProCore Needle	NCT01394159	Pancreatic Neop...	22G ProCore bio... 22G standard FN...	19 Years -	AdventHealth

Spots Global Cancer Trial Database for passes required to establish diagnosis