Neoplasms

Digestive System Diseases

All Conditions

Colonic Neoplasms

Colorectal Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Colonic Diseases

Intestinal Diseases

Reproductive Control Agents

All Drugs and Chemicals

Herbal and Botanical

Dinoprostone

Cola

Healthy People 2010 Diet using an exchange list

Mediterranean Diet using an exchange list

1 Healthy Eating

2 Mediterranean

Zora Djuric, Ph.D.

The purpose of this study is to help develop diets for colon cancer prevention. This study will compare the Mediterranean diet to the Healthy People 2010 diet in 120 subjects with increased risk for colorectal cancer.

There is substantial epidemiological evidence that dietary patterns influence colorectal cancer risk. The associations of any particular nutrient with increased or decreased risks, however, may not be due to that nutrient per se but to the whole foods that are rich in that nutrient. Simultaneously, reducing intakes of foods associated with increased risk while increasing foods identified in preventive diets may be the best approach for prevention. The Cretan-Mediterranean diet in particular appears to hold great promise for cancer prevention. The major components of the traditional Cretan diet have been associated with decreased colon cancer. Relative to the American diet, this diet has lower n-6/n-3 and n-6/n-9 fatty acid ratios, lower polyunsaturated fatty acid intake, lower red meat intake, and higher intakes of plant-based foods and monounsaturated fatty acids.

The hypothesis of this study is that adherence to a Mediterranean type of diet will result in a decrease in n-6 fatty acids and increased n-3 and n-9 fatty acids in human colorectal mucosa. This together with aspects of the diet such as increased intakes of fruits and vegetables, is expected to modulate eicosanoid metabolism and epithelial proliferation in normal mucosa. 120 persons, with an increased risk for colorectal cancer, will be randomized to a modified Mediterranean diet or a Healthy People 2010 diet for six months.

Healthy Eating for Colon Cancer Prevention

A Mediterranean Diet in Colon Cancer Prevention

Percentage of participants who met 70% of diet goals as outlined in the exchange list

University of Michigan

Research Professor

Healthy People 2010 Diet

Healthy People 2010 Diet through dietary counseling: 6 months telephone counseling

Mediterranean Diet

Mediterranean Diet through dietary counseling: 6 months telephone counseling

Healthy People 2010 Diet using an exchange list

1 Healthy Eating: 6 months telephone counseling

Mediterranean Diet using an exchange list

2 Mediterranean: 6 months telephone counseling

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Healthy Eating for Colon Cancer Prevention	NCT00475722	Colon Cancer	1 Healthy Eatin... 2 Mediterranean	21 Years -	University of Michigan
Healthy Eating for Colon Cancer Prevention	NCT00475722	Colon Cancer	1 Healthy Eatin... 2 Mediterranean	21 Years -	University of Michigan
Healthy Eating for Colon Cancer Prevention	NCT00475722	Colon Cancer	1 Healthy Eatin... 2 Mediterranean	21 Years -	University of Michigan

Spots Global Cancer Trial Database for pge2

Every month we try and update this database with for pge2 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for pge2

Every month we try and update this database with for pge2 cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for pge2 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.