Spots Global Cancer Trial Database for pleural effusion
Every month we try and update this database with for pleural effusion cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Liquid Biopsy With Immunomagnetic Beads Capture Technique for Malignant Cell Detection in Body Fluid | NCT02891642 | Malignancy Pleural Effusio... Pleural Disease... Ascites | Immunomagnetic ... | 18 Years - 80 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC) | NCT01999985 | Lung Cancer Non-small Cell ... | Dasatinib - 1A Afatinib - 1A Dasatinib - 1B Afatinib - 1B | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Video-assisted Hyperthermic Pleural Chemoperfusion vs Talc Pleurodesis for Refractory Malignant Pleural Effusions. | NCT01409551 | Safety of Inter... Efficacy of Int... Cost Effectiven... | VATS hypertherm... Bedside talc sl... | - 75 Years | Theagenio Cancer Hospital | |
| Liquid Biopsy With Immunomagnetic Beads Capture Technique for Malignant Cell Detection in Body Fluid | NCT02891642 | Malignancy Pleural Effusio... Pleural Disease... Ascites | Immunomagnetic ... | 18 Years - 80 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Novel Pleural Fluid, Biopsy and Serum Biomarkers for the Investigation of Pleural Effusions | NCT03661801 | Respiratory Dis... Pleural Effusio... Lung Cancer | 18 Years - | University of Oxford | ||
| Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma | NCT01722149 | Malignant Pleur... | Adoptive Transf... | 18 Years - 75 Years | University of Zurich | |
| Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy | NCT00858364 | Non-Small Cell ... Anemia Cancer Lung Cancer | Darbepoetin alf... Placebo | 18 Years - | Amgen | |
| Diaphragmatic Resection And Gynecological Ovarian Neoplasm | NCT03543462 | Ovarian Cancer | thoracic Drain ... | 18 Years - 80 Years | Catholic University of the Sacred Heart | |
| The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection | NCT01612975 | Pleural Effusio... Pleural Effusio... | Naproxen Placebo | 18 Years - 100 Years | McMaster University | |
| International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) | NCT03210298 | Peritoneum Canc... Peritoneum Neop... Pleural Cancer Pleural Effusio... Pleural Mesothe... Ovarian Cancer Gastric Cancer Appendix Cancer Pseudomyxoma Pe... Colorectal Canc... Pancreas Cancer Gallbladder Can... Ascites CUP Chemotherapeuti... | PIPAC | 10 Years - | University of Magdeburg | |
| International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) | NCT03210298 | Peritoneum Canc... Peritoneum Neop... Pleural Cancer Pleural Effusio... Pleural Mesothe... Ovarian Cancer Gastric Cancer Appendix Cancer Pseudomyxoma Pe... Colorectal Canc... Pancreas Cancer Gallbladder Can... Ascites CUP Chemotherapeuti... | PIPAC | 10 Years - | University of Magdeburg | |
| Minirigid Versus Conventional Rigid Thoracoscopy in Undiagnosed Pleural Effusions | NCT03449602 | Pleural Effusio... | Mini-thoracosco... Conventional ri... | 15 Years - 80 Years | PGIMER | |
| Talc Outpatient Pleurodesis With Indwelling Catheter | NCT03973957 | Pleural Effusio... Pleural Disease... Malignant Pleur... | Indwelling pleu... Fentanyl Citrat... Talc Slurry Drainage collec... | 18 Years - | The Cooper Health System | |
| MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung Cancer | NCT00799240 | Non Small Cell ... | Arm A: Pemetrex... Arm B Pemetrexe... | 18 Years - | University of Kansas Medical Center | |
| The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection | NCT01612975 | Pleural Effusio... Pleural Effusio... | Naproxen Placebo | 18 Years - 100 Years | McMaster University | |
| Retrospective Study of Carebot AI CXR Performance in Preclinical Practice | NCT05594485 | Artificial Inte... Lung Diseases Pneumothorax Pleural Effusio... Cardiomegaly Lung Cancer Pulmonary Edema Consolidation Pneumonia Atelectasis Hilar Calcifica... Fracture Rib | Carebot AI CXR | 18 Years - | Carebot s.r.o. | |
| Immune- and Microenvironment- Proteogenomics Profiling for Classifying Lung Cancer Patients | NCT04887545 | Lung Cancer Malignancy | Proteomics anal... | 18 Years - | Universidade Nova de Lisboa | |
| Comparing N-terminal-proB-type Natriuretic Peptide With Other Criteria in Pleural Fluid Analysis | NCT05797649 | Pleural Effusio... Heart Failure Malignant Neopl... Fluid Overload Hypoalbuminemia Renal Failure Cirrhosis Infections | 18 Years - | Chinese University of Hong Kong | ||
| PMCF Study of the CE-marked Drainova® ArgentiC Catheter | NCT06436807 | Pleural Effusio... Pleural Effusio... Ascites Ascites, Malign... | Indwelling cath... | 18 Years - | ewimed GmbH | |
| MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung Cancer | NCT00799240 | Non Small Cell ... | Arm A: Pemetrex... Arm B Pemetrexe... | 18 Years - | University of Kansas Medical Center | |
| The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection | NCT01612975 | Pleural Effusio... Pleural Effusio... | Naproxen Placebo | 18 Years - 100 Years | McMaster University | |
| Investigation Into the Automated Drainage of Recurrent Effusions From the Pleural Space in Thoracic Malignancy. | NCT01952327 | Pleural Effusio... | The pleurapump ... | 18 Years - | Sequana Medical N.V. | |
| The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion. | NCT03678090 | Pleural Effusio... Cancer, Lung | tPA standard do... tPA low dosage | 18 Years - | Yale University | |
| Using Pleural Effusions to Diagnose Cancer | NCT03319472 | Pleural Effusio... | 18 Years - | University of Patras | ||
| Collection of Pleural Effusion Fluid | NCT05539183 | Solid Tumor Pleural Effusio... Metastasis | Blood withdrawa... | 18 Years - | Universitair Ziekenhuis Brussel | |
| Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma | NCT01766739 | Lung Cancer | GL-ONC1 | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Early Intrapleural TPA Instillation Versus Late | NCT03167281 | Tissue Plasmino... | early tPA and D... | 18 Years - 100 Years | Prisma Health-Midlands | |
| Novel Pleural Fluid, Biopsy and Serum Biomarkers for the Investigation of Pleural Effusions | NCT03661801 | Respiratory Dis... Pleural Effusio... Lung Cancer | 18 Years - | University of Oxford | ||
| Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma | NCT01722149 | Malignant Pleur... | Adoptive Transf... | 18 Years - 75 Years | University of Zurich | |
| Diaphragmatic Resection And Gynecological Ovarian Neoplasm | NCT03543462 | Ovarian Cancer | thoracic Drain ... | 18 Years - 80 Years | Catholic University of the Sacred Heart | |
| Comparing N-terminal-proB-type Natriuretic Peptide With Other Criteria in Pleural Fluid Analysis | NCT05797649 | Pleural Effusio... Heart Failure Malignant Neopl... Fluid Overload Hypoalbuminemia Renal Failure Cirrhosis Infections | 18 Years - | Chinese University of Hong Kong | ||
| Using Pleural Effusions to Diagnose Cancer | NCT03319472 | Pleural Effusio... | 18 Years - | University of Patras | ||
| Comparison of Pleural Drainage Systems on Reducing Pleural Effusion Formation Following Lung Resection | NCT01776372 | Lung Neoplasms Pleural Effusio... | Medela Thopaz T... Atrium Express ... | 18 Years - 90 Years | McMaster University | |
| The First Therapeutic Intervention in Malignant Pleural Effusion Trial | NCT00896285 | Malignant Pleur... Pleural Effusio... | Large bore ches... Small bore ches... Large bore ches... Small bore ches... | 18 Years - | University of California, Davis | |
| Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma | NCT01766739 | Lung Cancer | GL-ONC1 | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| AI Assisted Detection of Chest X-Rays | NCT06075836 | Pulmonary Nodul... Pulmonary Nodul... Pulmonary Conso... Pneumothorax Pneumothorax; A... Atelectasis Pulmonary Calci... Cardiomegaly Fibrosis Lung Pleural Effusio... Pleural Effusio... Pneumoperitoneu... | Cases reading Ground truthing | - | Oxford University Hospitals NHS Trust | |
| Triplet Combination First Line Treatment in Non Small Cell Lung Cancer (NSCLC) | NCT00942825 | Metastatic Non-... | CBP501 + Cispla... Cisplatin + Pem... | 18 Years - | CanBas Co. Ltd. | |
| Screening of Postoperative Pulmonary Complications by Electrical Impedance Tomography | NCT02337673 | Pulmonary Disea... Postoperative R... Malignant Neopl... Liver Diseases Pancreatic Dise... | 18 Years - | Johannes Gutenberg University Mainz | ||
| Talc Outpatient Pleurodesis With Indwelling Catheter | NCT03973957 | Pleural Effusio... Pleural Disease... Malignant Pleur... | Indwelling pleu... Fentanyl Citrat... Talc Slurry Drainage collec... | 18 Years - | The Cooper Health System | |
| A Randomised Study Evaluating Diagnostics of Pleural Effusion Among Patients Suspect of Cancer. | NCT04233359 | Pleural Effusio... Pleural Effusio... Pleura; Exudate | Local anestheti... US-guided pleur... | 18 Years - | Naestved Hospital | |
| Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC) | NCT01999985 | Lung Cancer Non-small Cell ... | Dasatinib - 1A Afatinib - 1A Dasatinib - 1B Afatinib - 1B | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Safety and Effectiveness Study of Tumor Cell-derived Microparticles to Treat Malignant Ascites and Pleural Effusion | NCT01854866 | Malignant Pleur... Malignant Ascit... | Drug-packaging ... | 18 Years - 70 Years | Huazhong University of Science and Technology | |
| The Effectiveness and Safety of Ultrasound Elastography Guided Pleural Biopsy in the Differential Diagnosis of Benign and Malignant Pleural Effusion | NCT05781659 | Pleural Effusio... | Ultrasound elas... Traditional ult... | 18 Years - 90 Years | China-Japan Friendship Hospital | |
| Data Visualization of Kidney and Prostate Tumors Using Routine Pre-Operative Imaging, 3D Printed, and 3D Virtual Reality Models | NCT03656822 | Pleural Effusio... | Routine CT Routine imaging... Routine imaging... Routine MRI Routine imaging... Routine imaging... | 18 Years - 100 Years | NYU Langone Health | |
| Pleural Ultrasonography in Lung Cancer | NCT01141946 | Lung Cancer | thoracic ultras... pleural aspirat... | 18 Years - | Centre hospitalier de l'Université de Montréal (CHUM) | |
| Medical Thoracoscopy for Diagnosing Unexplained Pleural Effusion: a National Multicenter Retrospective Study | NCT06275178 | Pleural Effusio... Pleural Effusio... Fibrinous Pleur... | Medical thoraco... | 18 Years - 80 Years | China-Japan Friendship Hospital | |
| AI Assisted Detection of Chest X-Rays | NCT06075836 | Pulmonary Nodul... Pulmonary Nodul... Pulmonary Conso... Pneumothorax Pneumothorax; A... Atelectasis Pulmonary Calci... Cardiomegaly Fibrosis Lung Pleural Effusio... Pleural Effusio... Pneumoperitoneu... | Cases reading Ground truthing | - | Oxford University Hospitals NHS Trust | |
| Interventions for Malignant Pleural Effusions Impact on Fatigue | NCT04793607 | Malignant Pleur... | Pleural procedu... | 18 Years - | Northumbria Healthcare NHS Foundation Trust | |
| Multicenter Observational Study of Advanced Non-small Cell Lung Cancer With Malignant Pleural Effusion | NCT04263688 | Non-Small Cell ... | Non-Interventio... | 18 Years - | Guangzhou Institute of Respiratory Disease | |
| Multi-Reader Retrospective Study Examining Carebot AI CXR 2.0.21-v2.01 Implementation in Everyday Radiology Clinical Practice | NCT05963945 | Pneumothorax Pulmonary Nodul... Atelectasis Subcutaneous Em... Cardiomegaly Consolidation Pleural Effusio... | Carebot AI CXR | 18 Years - | Carebot s.r.o. | |
| Intrapleural Catheter Daily Versus Three Times a Week Drainage | NCT00761618 | Advanced Cancer Pleural Effusio... | Intrapleural ca... IPC Placement Chest X-Ray | 18 Years - | M.D. Anderson Cancer Center | |
| Use of Guidance Videos to Increase Engagement and Decrease Anxiety in Patients Undergoing Pleural Tap | NCT04254445 | Pleural Effusio... Pleural Effusio... Pleural Pleuris... | Personalized tr... | 18 Years - 99 Years | GistMed Ltd. | |
| Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy | NCT00858364 | Non-Small Cell ... Anemia Cancer Lung Cancer | Darbepoetin alf... Placebo | 18 Years - | Amgen | |
| Yield of Cryoprobe vs Flexible Forceps Pleural Biopsy | NCT02500277 | Pleural Effusio... Pleurisy Tuberculosis Metastatic Mali... | Cryoprobe pleur... Flexible forcep... | 12 Years - 79 Years | PGIMER | |
| Value of Additional Upfront Systematic Lung Ultrasound in the Workup of Patients With Unilateral Pleural Effusion | NCT04235998 | Pleural Effusio... Malignant Pleur... Ultrasound | Systematic lung... | 18 Years - | Naestved Hospital |
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