Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Breast Neoplasms

Infertility

Breast Diseases

Skin Diseases

Study of spontaneous fertility outcomes following breast cancer history

Study of spontaneous fertility outcomes in healthy volonteers population

Longitudinal observational study. Collection of health data using self-administered questionnaires online.

questionnaires

Laura SABLONE

Fabien REYAL, MD

Charles CHAPRON, Pr

Marc ESPIE, MD

Isabelle RAY-COQUARD, Pr

Audrey MAILLIEZ, MD

Claire SENECHAL, MD

Anne-Sophie HAMY-PETIT, MD

FErtility, PrEgnancy, contRaceptIon after breast Cancer in France

Breast cancer is the most common cancer among women. With the increase of the survival rates, a growing attention is paid to the side effects of the treatments, particularly chemotherapy-induced infertility.

The FEERIC study will give insights into spontaneous fertility outcomes following breast cancer in comparison with a control cohort and will provide data to help patients counselling towards spontaneous fertility rates following breast cancer. It will also provide data on contraceptive prevalence and unintended pregnancy rates in French breast cancer survivors. Reasons for unmet need for family planning will be deciphered, in order to point out pitfalls (lack of patient's information or orientation/ignorance of contraception methods available/topic insufficiently or not discussed with the physician/ lack of family planning offer etc...); and target the appropriate actions to lead (oncologist and oncology nurses education/ dedicated consultations in breast cancer centers/etc...).

FErtility, PrEgnancy, contRaceptIon After Breast Cancer in France

FErtility, PrEgnancy, contRaceptIon After Breast Cancer in France: the FEERIC Study

Odds ratio between the spontaneous pregnancies between cases and controls, for women with a desire to become pregnant and trying to get pregnant.

Time to spontaneous pregnancy after breast cancer diagnosis, for women with a desire to become pregnant and trying to get pregnant.

Contraceptive use, defined as the percentage of women reporting use of a contraceptive method.

An unwanted pregnancy is defined as unwanted at the time of conception. Women are classified as at risk of unwanted pregnancy if they report having had unprotected sex without a desire to become pregnant in the previous four months.

Percentages live births obtained by ARTs procédures, that include in vitro fertilization (IVF) and embryo transfer (ET), intracytoplasmic sperm injection (ICSI) and ovarian stimulation with exogenous gonadotropins.

seintinelles network

Institut Curie

Symptoms and General Pathology

Musculoskeletal Diseases

Immune System Diseases

Infections

Mouth and Tooth Diseases

Eye Diseases

Nervous System Diseases

Heart and Blood Diseases

Rare Diseases

Syndrome

Scleroderma, Systemic

Scleroderma, Diffuse

Arthritis

Arthritis, Rheumatoid

Mastocytosis

Spondylitis

Sjogren's Syndrome

Arthritis, Psoriatic

Lupus Erythematosus, Systemic

Spondylarthritis

Myositis

Vasculitis

Antiphospholipid Syndrome

Joint Diseases

Rheumatic Diseases

Collagen Diseases

Connective Tissue Diseases

Autoimmune Diseases

Spondylarthropathies

Spinal Diseases

Bone Diseases

Psoriasis

Skin Diseases, Papulosquamous

Xerostomia

Salivary Gland Diseases

Mouth Diseases

Stomatognathic Diseases

Dry Eye Syndromes

Keratoconjunctivitis Sicca

Lacrimal Apparatus Diseases

Vascular Diseases

Disease Attributes

Neoplasms, Connective Tissue

Neoplasms, Connective and Soft Tissue

Neoplasms by Histologic Type

Mast Cell Activation Disorders

Muscular Diseases

Neuromuscular Diseases

Systemic Scleroderma

Idiopathic Inflammatory Myopathy

Spondylarthropathy

Nathalie Costedoat-Chalumeau, PhD

Adèle Bellino

nathalie Costedoat-Chalumeau, PhD

Rare diseases frequently affect women of childbearing age. Pregnancy in these women has become less rare, but remains associated with high levels of complications. One obstacle to their optimal management during pregnancy is that there are no prospective studies of pregnancy during rare diseases and several connective tissue diseases. As a consequence, the management of these pregnancies is non-standardised in terms of treatment, monitoring (frequency of consultations, laboratory tests and ultrasound), and organisation of care.

Moreover, although these women (all diseases combined) are frequently exposed to medications potentially incompatible with pregnancy, little is known about the frequency of these exposures and especially their consequences to mother and child.

For these reasons, researchers and clinicians from different specialties created an interdisciplinary research group on pregnancy and rare diseases (GR2), intended to improve the management of these patients' pregnancies. Using a single computer server, the investigators plan to set up a large prospective study of pregnancies in patients with rare diseases: various forms of myositis, lupus, antiphospholipid syndrome, Sjogren syndrome, scleroderma, and inflammatory rheumatic diseases. The investigators objective is to analyse the complications of pregnancies in women with rare diseases and then to improve their management and their quality of life.

Pregnancy and Medically Assisted Conception in Rare Diseases

Prospective Observational Study About Pregnancy and Medically Assisted Conception in Rare Diseases

It's a composite outcome . A pregnancy with no severe maternal complication (by the Epimoms\* definition), live birth after 35 weeks' gestation, a birth weight \>10th percentile of the general population and no infections (maternal and infant) during pregnancy and first year of follow up, respectively

About the organisation of care (analysis of the effect on outcome of the number of ultrasound examinations and clinician visits, and the systematic planning of delivery)

Analyse the frequency of exposure to various medications (immunosuppressors, biological therapy, corticosteroids) and their maternal and fetal consequences (e.g., infectious complications).

Within an existing collection with (1) samples taken during the first trimester of pregnancy to analyse markers that might predict subsequent obstetric complications (cytokines, growth factors, enzymes) (2) with cord blood samples (which will, in particular, enable immunological and pharmacological analyses).

SNFMI

CRAT

Assistance Publique - Hôpitaux de Paris

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
FErtility, PrEgnancy, contRaceptIon After Breast Cancer in France	NCT03884413	Breast Cancer F...	questionnaires	18 Years - 43 Years	Institut Curie
Pregnancy and Medically Assisted Conception in Rare Diseases	NCT02450396	Rheumatoid Arth... Spondyloarthrit... Psoriatic Arthr... Systemic Lupus ... Antiphospholipi... Sjogren Syndrom... Scleroderma Myositis Vasculitis Mastocytosis Various Autoimm...		-	Assistance Publique - Hôpitaux de Paris
Pregnancy and Medically Assisted Conception in Rare Diseases	NCT02450396	Rheumatoid Arth... Spondyloarthrit... Psoriatic Arthr... Systemic Lupus ... Antiphospholipi... Sjogren Syndrom... Scleroderma Myositis Vasculitis Mastocytosis Various Autoimm...		-	Assistance Publique - Hôpitaux de Paris

Spots Global Cancer Trial Database for pregnancy,

Every month we try and update this database with for pregnancy, cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for pregnancy,

Every month we try and update this database with for pregnancy, cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for pregnancy, cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.