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Using Hepatectomy for the treatment of advanced HCC

Ablating the liver tissue around the tumor before hepatectomy.

Using RFA to ablate and block the small vessels around the tumor before resection to reduce the spreading of the cancer cell.

RFA assisted Hepatectomy

Treat the advanced HCC with the hepatectomy only.

Hepatectomy

Kai Feng, M.D

Kuansheng Ma, Ph.D

RFA has become a standard method in the treatment of small HCC(≤2 cm) due to its ease of use, safety, cost-effectiveness, and minimal invasiveness. It can ablated and blocked the small vessels while destroyed the tumor cell in situ. Surgical resection is the most widely accepted treatment for the patients with advanced hepatocellular carcinoma in the Asian countries. But the effectiveness of hepatectomy was depressed because of the high recurrence rate. The spreading of the cancer cell along the portal vein or the hepatic vein system during the operation account for the tumor recurrence. Using RFA to ablate and block the small vessels around the tumor before resection will reduce the spreading of the cancer cell. Investigators hypothesized that the RFA assisted hepatectomy might result in lower recurrence rate than hepatectomy alone in the treatment of advanced HCC. Thus, the purpose of this study was to prospectively compare the effects of RFA assisted hepatectomy with hepatectomy alone for the treatment of advanced HCC.

Radiofrequency Ablation Assisted Hepatectomy Versus Hepatectomy Alone for Advanced Hepatocellular Carcinoma

A Randomized Controlled Trial of Radiofrequency Ablation Assisted Hepatectomy and Hepatectomy Alone in the Treatment of Advanced Hepatocellular Carcinoma

Southwest Hospital, China

Institute of Hepatobiliary Surgery

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Radiofrequency Ablation Assisted Hepatectomy Versus Hepatectomy Alone for Advanced Hepatocellular Carcinoma	NCT01713244	Hepatocellular ...	RFA assisted He... Hepatectomy	18 Years - 70 Years	Southwest Hospital, China
Radiofrequency Ablation Assisted Hepatectomy Versus Hepatectomy Alone for Advanced Hepatocellular Carcinoma	NCT01713244	Hepatocellular ...	RFA assisted He... Hepatectomy	18 Years - 70 Years	Southwest Hospital, China

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