Neoplasms

All Conditions

Rare Diseases

Glioblastoma

Gliosarcoma

Astrocytoma

Glioma

Neoplasms, Neuroepithelial

Neuroectodermal Tumors

Neuroectodermal Tumors, Primitive

Neoplasms, Germ Cell and Embryonal

Neoplasms by Histologic Type

Neoplasms, Glandular and Epithelial

Neoplasms, Nerve Tissue

Neuroepithelioma

Surgical tumor resection as standard of care and specimen collection

Collect and preserve glioblastoma tissue for exploratory analyses to generate hypotheses for future studies.

Specimen Collection

Manmeet S Ahluwalia, M.D.

Michael McDermott, M.D.

To collect and preserve glioblastoma tissue during standard of care tumor resection surgery and blood for future molecular and genetic testing. Tissue for research will be collected from three different regions within the same tumor to study how these regions differ in their structure, DNA, and RNA and also to compare the data obtained from this testing to imaging data found in the medical record. The goal of this study is to help us better understand what the glioblastoma tumor tissue looks like and how it functions. This understanding can lead to new therapies for the treatment of glioblastoma in the future.

Blood: 50 mL (less than 4 tablespoons) Glioblastoma tissue: three geographically distinct samples from the same tumor, about 10 cubic centimeters in volume

Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue

Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue (PRESERVE GBM)

Total number of GBM samples collected and preserved for analysis

Miami Cancer Institute

Nico Corporation

Baptist Health South Florida

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue	NCT05756985	Glioblastoma Glioblastoma Mu... Gliosarcoma	Specimen Collec...	18 Years -	Baptist Health South Florida
Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue	NCT05756985	Glioblastoma Glioblastoma Mu... Gliosarcoma	Specimen Collec...	18 Years -	Baptist Health South Florida

Spots Global Cancer Trial Database for specimen banking