Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Behaviors and Mental Disorders

Breast Neoplasms

Breast Diseases

Skin Diseases

Quality of Life

10 weekly 2-hour sessions of group-based cognitive behavioral stress management

a single day group-based psycho-educational seminar

Cognitive Behavioral Stress Management

a psycho-educational control

Michael Antoni, Ph.D.

The purpose of this study is to test the effects of a 10-wk cognitive behavioral stress management (CBSM) intervention vs. a single-day psycho-educational seminar on psychosocial adaptation and physiological adaptation in women being treated for stage I-III breast cancer.

The study tests the effects of a 10-wk group-based cognitive behavioral stress management (CBSM) intervention (relaxation, stress awareness, cognitive restructuring, coping skills training, interpersonal skills training) versus a single-day psycho-educational seminar (general information about stress and coping) in women who have recently had surgery for breast cancer but have not yet started adjuvant therapy. The study evaluates the effects of CBSM on psychosocial adaptation (includes measures of negative adaptation \[distress and social disruption\] and positive adaptation \[benefit finding and positive affect\]) at 6-month and 12-month follow-up. The study also evaluates the effects of CBSM on physiological adaptation (includes levels of PM serum cortisol and T-helper-type 1 (Th1) cytokine \[interleukin-2, IL-2, and interferon-gamma, IFN-g, production after anti-CD3 stimulation of peripheral blood mononuclear cells (PBMC).

Facilitating Positive Adaptation to Breast Cancer

changes in a composite composed of negative affect measures plus a measure of social disruption plus a measure of benefit finding plus a measure of positive affect

decreased PM levels of serum cortisol and increased Th1 (interleukin-2, interferon-gamma) cytokine production following anti-CD3 stimulation of peripheral blood mononuclear cells (PBMCs)

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Facilitating Positive Adaptation to Breast Cancer	NCT01422551	Breast Cancer	Cognitive Behav... a psycho-educat...	21 Years - 75 Years	University of Miami
Facilitating Positive Adaptation to Breast Cancer	NCT01422551	Breast Cancer	Cognitive Behav... a psycho-educat...	21 Years - 75 Years	University of Miami

Spots Global Cancer Trial Database for stress management intervention