Neoplasms

Digestive System Diseases

All Conditions

Symptoms and General Pathology

Rare Diseases

Esophageal Neoplasms

Constriction, Pathologic

Gastrointestinal Neoplasms

Digestive System Neoplasms

Head and Neck Neoplasms

Gastrointestinal Diseases

Esophageal Diseases

Esophageal Cancer

hybrid everted esophagogastric anastomosis

the conventional hand-sewn anastomosis

a stapled anastomosis

Qi L Chen

The investigators improved the hybrid everted esophagogastrostomy and expected to prevent the incidence of anastomotic stricture. The purpose of this study is to determine the clinical value of this kind of operation type, and analyzes the clinicopathological factors causing the postoperative complications.

This randomized clinical trial compared a hybrid everted esophagogastric anastomosis with conventional hand-sewn or stapled esophagogastrostomy for prevention of anastomotic stricture. The patients were completely randomized to receive either a hybrid everted esophagogastric anastomosis (HE group), or the conventional hand-sewn (HS group), or a stapled (SA group) anastomosis, after the removal of esophageal tumor. The primary outcome measured the incidence of anastomotic stricture at 3 months after the operation (defined as the diameter of the anastomotic orifice \<= 0.8 cm on esophagogram), analyzed by intention-to-treat.

Hybrid-everted Versus Hand-sewn or Stapled Esophagogastrostomy in Prevention of Anastomotic Stricture

Phase III Study of Hybrid-everted Versus Hand-sewn of Stapled Esophagogastrostomy in Prevention of Anastomotic Stricture

the anastomotic stricture is defined as the diameter of the anastomotic orifice \<= 0.8 cm on esophagogram

0:No dysphagia on solid diet

1. dysphagia on solid diet
2. dyspahgia on semi-solid diet
3. dysphagia on fluid diet
4. dysphagia with water swallowing

0:no reflux on semi-supine position

1. postprandial reflux on semi-supine position
2. reflux with empty stomatch on semi-supine position
3. postprandial reflux on upright position
4. reflux with empty stomach on upright positino

Sichuan University

Long-Qi Chen, Professor

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Hybrid-everted Versus Hand-sewn or Stapled Esophagogastrostomy in Prevention of Anastomotic Stricture	NCT01139229	Esophageal Neop... Surgical Stomas	hybrid everted ... the conventiona... a stapled anast...	-	Sichuan University
Hybrid-everted Versus Hand-sewn or Stapled Esophagogastrostomy in Prevention of Anastomotic Stricture	NCT01139229	Esophageal Neop... Surgical Stomas	hybrid everted ... the conventiona... a stapled anast...	-	Sichuan University

Spots Global Cancer Trial Database for surgical stomas