Symptoms and General Pathology

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Patients with haematological malignancy Conventional haematological care

Patients with haematological malignancy Conventional care associated with a monthly consultation realized by a palliative and supportive care team

The follow-up time for each patient is 12 months with evaluation of the main objective by a standardized questionnaire: The Functional Assessment of Cancer Therapy-Anaemia (FACT-An) Scale at 6 months. Throughout the study, patients included will receive conventional haematological care and the interventional arm will benefit in addition to a monthly consultation by a palliative care team.

Early palliative care integration

Lise LACLAUTRE

Laurent SUTTON

Matthieu CRETINON

Virginie GUASTELLA

Jacques-Olivier BAY

Stéphane MOREAU

Bertrand SARDIN

Anne-Sophie MICHALLET

Gisèle CHVETZOF

Denis GUYOTAT

Stéphanie MORISSON

Karine SOULIER-GUERIN

Franck DELPRETTI

Patients suffering from haematological disease present symptoms of discomfort and currently benefit from palliative care skills only for the management of their end-of-life. However, in medical oncology, more and more studies tend to demonstrate the benefit on the quality of life of an early collaboration between the two specialties.

Investigator did the hypothesis that early integration of palliative care with conventional haematological care could decrease discomfort symptoms and add a real benefit on the patients' quality of life .

Early Palliative Care for Patients With Haematological Malignancies

Early Palliative Care for Patients With Haematological Malignancies: A Randomised Prospective Study

Evaluation of quality of life by a standardized questionnaire : Functional Assessment of Cancer Therapy-Anemia (FACT-An). The higher is the score the better is the quality of life. FACT-An is composed by five subscales: Physical Well-Being \[score range 0-28\], Social/Family Well-Being \[score range 0-28\], Emotional Well-Being \[score range 0-24\], and Functional Well-Being \[score range 0-28\] and specific questions concerning anemia \[score range 0-80\]. The score at each items is summed. The sum is multiplied par the number of items in the subscale and then divided by the number of items answered. This produces the subscale score. The subscale scores are added to derive total score \[score range 0-188\].

evaluated by Edmonton scale (depressive syndrome measured by the geriatric depression scale GDS)

matching between patients desires writing in the medical file and the providing care

The cost criteria selected will be all the direct medical costs inherent in care in both arms (costs of hospitalizations, consultations, treatments, medical devices).

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Early Palliative Care for Patients With Haematological Malignancies	NCT03800095	Acute Myeloid L... Myelodysplastic... Diffuse Large B... Palliative Care	Early palliativ...	70 Years -	University Hospital, Clermont-Ferrand
Early Palliative Care for Patients With Haematological Malignancies	NCT03800095	Acute Myeloid L... Myelodysplastic... Diffuse Large B... Palliative Care	Early palliativ...	70 Years -	University Hospital, Clermont-Ferrand

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