Neoplasms

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Multiple Myeloma

Neoplasms, Plasma Cell

Neoplasms by Histologic Type

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Vulnerability and therapeutic changes in older patients with multiple myeloma.

Komivi AGBETSIVI, DR

VIGNARD Patricia, Dr

Catherine Cattenoz, Dr

Jean -Richard EVEILLARD, Dr

François Puisieux, Pr

Jean -Yves NIEMIER, Dr

Frédérique Retornaz, Dr

Véronique Brunel, Dr

Laure De Decker, Dr

The aim of this study is to determine whether the presence of vulnerability detected by geriatricians is associated with treatment discontinuation in older patient. During the comprehensive geriatric assessment realized before the decision-treatment, the following data are recorded and their impact in the therapeutic changes will also be analysed: comorbidity, age, depression, functional status, the cognitive impairment and malnutrition.

Vulnerability and Therapeutic Changes in Older Patients With Multiple Myeloma.

The primary outcome is either :

* early interruption of treatment
* dose reduction \> 20% during treatment
* discontinuous treatment

These outcomes will be measured every 6 months during the 2 years of follow up

vulnerability related to toxicities, vulnerability related to multiple myeloma or geriatric vulnerability.

early interruption of treatment, dose reduction during treatment, discontinuous treatment

hematologic toxicity, neurotoxicity, gastrointestinal toxicity, deep vein thrombosis, pulmonary embolism, infections with antibiotic use

Nantes University Hospital

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Vulnerability and Therapeutic Changes in Older Patients With Multiple Myeloma.	NCT02063113	Multiple Myelom...	Vulnerability a...	70 Years - 100 Years	Nantes University Hospital
Vulnerability and Therapeutic Changes in Older Patients With Multiple Myeloma.	NCT02063113	Multiple Myelom...	Vulnerability a...	70 Years - 100 Years	Nantes University Hospital

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Spots Global Cancer Trial Database for treatment,

Every month we try and update this database with for treatment, cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for treatment, cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.