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Brief Title: Pharmacokinetics and Dynamics of Nebulized Dexmedetomidine
Official Title: Pharmacokinetics and Dynamics of Nebulized Dexmedetomidine in Preschool Children Undergoing Abdominal Cancer Surgery
Study ID: NCT03762785
Brief Summary: the aim of this study is to study the pharmacokinetics and dynamics of nebulized dexmetedomidine in children undergoing major abdominal cancer surgery.
Detailed Description: Inhalation of nebulized drug is an alternative route of administration that is relatively easy to set up, does not require venpuncture, but is associated with high bioavailability of the administered drug. Information on the pharmacokinetics of dexmedetomidine in the pediatric population is very limited, especially in children. To the best of investigators knowledge, there are no published reports on the pharmacokinetics of nebulized dexmedetomidine in children.
Minimum Age: 3 Years
Eligible Ages: CHILD
Sex: ALL
Healthy Volunteers: No
South Egypt Cancer Institute, Assiut, , Egypt
Name: Shereen M Kamal, Lecturer
Affiliation: Ministry of higher education
Role: PRINCIPAL_INVESTIGATOR