Spots Global Cancer Trial Database for Umbilical Cord Blood Transplantation From Unrelated Donors
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Trial Identification
Brief Title: Umbilical Cord Blood Transplantation From Unrelated Donors
Official Title: Umbilical Cord Blood Transplantation From Unrelated Donors
Study ID: NCT03016806
Study Description
Brief Summary: This study is a single-center, treatment protocol with 4 possible preparative regimens, designed to validate the process of umbilical cord blood stem cell transplantation at our institution.
Detailed Description: This study is a single-center treatment protocol with four possible preparative regimens, designed to validate the process of umbilical cord blood stem cell transplantation at our institution. Enrolled patients will receive chemotherapy +/-total body radiation as a pre-transplant conditioning regimen. Patients will then receive cord blood stem cells followed by GvHD prophylaxis that will include Tacrolimus and Mycophenolate Mofetil, or Cyclosporin A and Methylprednisolone. Multiple data points will be collected prior to, during, and following transplantation to ensure safety of the process and to evaluate the stated objectives.
Keywords
Eligibility
Minimum Age: 2 Months
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Wilmot Cancer Institute, Rochester, New York, United States
Contact Details
Name: Jane L Liesveld, MD
Affiliation: Medical Director, Blood & Marrow Transplant Unit
Role: PRINCIPAL_INVESTIGATOR
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