Spots Global Cancer Trial Database for Determining the Mechanisms of Loss of CAR T Cell Persistence
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Trial Identification
Brief Title: Determining the Mechanisms of Loss of CAR T Cell Persistence
Official Title: Determining the Mechanisms of Loss of CAR T Cell Persistence
Study ID: NCT05809284
Interventions
Study Description
Brief Summary: A prospective observational study of pediatric and young adult acute lymphoblastic leukaemia (ALL) patients treated with CD19 chimeric antigen receptor T-cells (CAR-T cells). The study will examine changes in CAR-T persistence over time and causal factors.
Detailed Description:
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Great Ormond Street Hospital, London, , United Kingdom
University College London Hospital, London, , United Kingdom
Royal Manchester Children's Hospital, Manchester, , United Kingdom
Contact Details
Name: Persis Amrolia, BSc,MBBS,PhD
Affiliation: UCL Institute of Child Health
Role: STUDY_CHAIR
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