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Brief Title: Multicentric Registry of Patients With Acute Leukemia Infected by COVID-19
Official Title: National Retrospective Monitoring of Patients With Acute Leukemia Infected by COronaVirus Disease 2019 (COVID-19)
Study ID: NCT04452604
Brief Summary: The COVID-19 epidemic (Coronavirus Disease 2019) currently raging in France is an emerging infectious disease linked to a virus of the genus coronavirus (SARS-CoV-2). Epidemiologically, acute myeloblastic leukemias (AML) are the most common of acute leukemias. The incidence of acute lymphoblastic leukemia (ALL) is 900 new cases in France in 2018, of which 57% in humans. The treatments administered to AML and ALL patients induce variable immunosuppression: neutropenia, neuropathy, deficits in humoral or cellular immunity or combinations of these deficits. Patients with AML or ALL therefore represent a population at high risk of developing a serious form in the event of infection with SARS-CoV-2. To date, no data is available in the literature to assess the impact of the COVID-19 epidemic in the population of patients with acute leukemia. The main objective of the study is to determine the clinical and biological prognostic factors during SARS-CoV-2 infection in patients with acute leukemia.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Chu Amiens, Amiens, , France
CHU ANGERS - Maladies du sang, Angers, , France
Ch Avignon, Avignon, , France
CH de la Côte Basque - Hématologie, Bayonne, , France
CHU Caen - IHBN - Hématologie Clinique, Caen, , France
Centre Hospitalier Sud Francilien, Corbeil-essonnes, , France
Centre Hospitalier de Dunkerque, Dunkerque, , France
CHU de Grenoble - Hopital Michallon, Grenoble, , France
Centre Hospitalier du Mans, Le Mans, , France
Hôpital Saint Vicent de Paul, Lille, , France
Chu Limoges, Limoges, , France
Institut Paoli-Calmettes - Hématologie 2, Marseille, , France
HOPITAL SAINT ELOI - Hematologie, Montpellier, , France
HOPITAL E. MULLER - Hématologie, Mulhouse, , France
CHU HOTEL DIEU - Hématologie Clinique, Nantes, , France
CHU Caremeau, Nîmes, , France
CENTRE HOSPITALIER SAINTJEAN - Hématologie Clinique, Perpignan, , France
Bordeaux Pessac, Pessac, , France
Centre Hospitalier Lyon Sud, Pierre-Bénite, , France
CHU Reims - Hôpital Robert Debré - Hématologie Clinique, Reims, , France
CHU Pontchaillou - Hématologie, Rennes, , France
Chu de La Reunion - Site Sud, Saint-pierre, , France
Institut de Cancérologie Lucien Neuwirth, Saint-Priest-en-Jarez, , France
Institut Universitaire du Cancer de Toulouse Oncopole - Service d'Hématologie, Toulouse, , France
CHU de Brabois, Vandœuvre-lès-Nancy, , France
Centre Hospitalier de Versailles, Versailles, , France
Institut Gustave Roussy, Villejuif, , France
Name: Pierre-Yves DUMAS, Dr
Affiliation: French Innovative Leukemia Organisation
Role: PRINCIPAL_INVESTIGATOR