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Brief Title: Relapse Prophylaxis With N-803 for AML and MDS Pts Following Allo HSCT
Official Title: Relapse Prophylaxis With IL-15 Super Agonist N-803 in Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome Following Reduced Intensity Conditioning (RIC) Allogeneic Stem Cell Transplantation
Study ID: NCT02989844
Brief Summary: This is a single-arm, multi-center Phase II trial using IL-15 super-agonist complex (N-803 formerly known as Alt-803) maintenance after allogeneic hematopoietic cell transplant (alloHCT) for acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, United States
Name: Claudio Brunstein, MD, PhD
Affiliation: University of Minnesota
Role: PRINCIPAL_INVESTIGATOR