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Brief Title: P3 Study of Umbilical Cord Blood Cells Expanded With MPCs for Transplantation in Patients With Hematologic Malignancies
Official Title: A 1-Year, Multicenter, Randomized, Open-Label Controlled Study to Evaluate the Efficacy and Safety of Cord Blood Cells Expanded With MPCs for Hematopoetic Recovery in Patients With Hematologic Malignancies After Myeloablative Treatment
Study ID: NCT01854567
Brief Summary: The study investigates the time to engraftment of a mesenchymal expanded cord blood unit in patients with hematologic malignancies undergoing transplantation with myeloablative conditioning.
Detailed Description:
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Miami Health System Sylvester Comprehensive Cancer Center, Miami, Florida, United States
Moffitt Cancer Center, Tampa, Florida, United States
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Weill Cornell-New York Presbyterian Hospital, New York, New York, United States
Westchester Medical Center, Valhalla, New York, United States
Case Western, Cleveland, Ohio, United States
MD Anderson Cancer Center, Houston, Texas, United States
Texas Transplant Center at Methodist Healthcare System, San Antonio, Texas, United States
Name: Donna Skerrett, MD, MS
Affiliation: Mesoblast, Ltd.
Role: STUDY_DIRECTOR
Name: Elizabeth J. Shpall, MD
Affiliation: M.D. Anderson Cancer Center
Role: PRINCIPAL_INVESTIGATOR