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Brief Title: T-Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Hematologic Malignancies
Official Title: T-Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Hematologic Malignancies
Study ID: NCT00683046
Brief Summary: Objectives: 1. To evaluate disease free survival after Campath 1H-based in vivo T-cell depletion and non-myelo-ablative ablative stem cell transplantation in patients with hematologic malignancies. 2. To evaluate the incidence and severity of acute and chronic GVHD after Campath 1H-based in vivo T-cell depletion, in patients with hematologic malignancies undergoing non-myelo-ablative stem cell transplantation. 3. To evaluate engraftment and chimerism after Campath 1H-based in vivo T-cell depletion and non-myelo-ablative ablative stem cell transplantation in patients with hematologic malignancies.
Detailed Description:
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The University of Chicago, Chicago, Illinois, United States
Name: Andrew Artz, MD
Affiliation: University of Chicago
Role: PRINCIPAL_INVESTIGATOR