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Brief Title: Safety, Tolerability and PK of AZD1152 in Patients With Relapsed Acute Myeloid Leukaemia (AML)
Official Title: A Phase I, Open Label, Multi-centre Study to Assess the Safety, Tolerability, and Pharmacokinetics of AZD1152 in Japanese Patients With Acute Myeloid Leukaemia.
Study ID: NCT00530699
Brief Summary: The purpose of this study is to assess safety and tolerability of multiple ascending doses of AZD1152 and to assess effect of AZD1152 on the rate of complete remission in patients with relapsed acute myeloid leukaemia who are not considered to be suitable for standard chemotherapy.
Detailed Description:
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Nagoya, Aichi, Japan
Research Site, Yoshida-gun, Fukui, Japan
Research Site, Maebashi-city, Gunma, Japan
Research Site, Isehara, Kanagawa, Japan
Research Site, Yokohama, Kanagawa, Japan
Research Site, Chuo, Tokyo, Japan
Research Site, Fukuoka, , Japan
Name: Paul Stockman
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR