Spots Global Cancer Trial Database for A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome
Official Title: Phase 1/Phase 2 Study of IMM01 Combined With Azacitidine in Patients With AML and MDS
Study ID: NCT05140811
Study Description
Brief Summary: This trial is an open-lable , multi-center, Phase 1/Phase 2 study that will evaluate the safety, tolerability, Pharmacokinetics, Pharmacodynamics and and immunogenicity of IMM01 combined with Azacitidine in patients with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS).
Detailed Description: Main study purpose: * To evaluate the safety and tolerability of IMM01 combined with Azacitidine in patients with AML and MDS. * To explore the Maximum Tolerated Dose (MTD) of IMM01 combined with Azacitidine, and determine the phase 2 clinical recommended dose (RP2D) of IMM01 combined with Azacitidine. Secondary study purpose: * To evaluate the efficacy of IMM01 combined with Azacitidine in patients with AML and MDS. * To evaluate the Pharmacokinetics and Pharmacodynamics of IMM01 combined with Azacitidine, in patients with AML and MDS. Exploratory study purpose: • To evaluate the immunogenicity of IMM01 combined with Azacitidine in patients with AML and MDS.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Beijing gobroad boren hospital, Beijing, , China
Peking university third hospital, Beijing, , China
Xuanwu Hospital, Capital Medical University, Beijing, , China
Chongqing university cancer hospital, Chongqing, , China
Second Affliated Hospital of Army Medical University, Chongqing, , China
Fujian medical university union hospital, Fuzhou, , China
Ganzhou People's Hospital, Ganzhou, , China
Guangdong provincial people hospital, Guangzhou, , China
Nanfang Hospital, Southern Medical University, Guangzhou, , China
Zhujiang Hospital, Southern Medical University/The Second School of Clinical Medicine, Southern Medical University, Guangzhou, , China
The first affiliated hospital zhejiang university school of medicine, Hangzhou, , China
The first affiliated hospital of nanchang University, Nanchang, , China
Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, , China
Shanghai sixth's hospital, Shanghai, , China
Tongren hospital shanghai jiaotong university school of medicine, Shanghai, , China
Shengjing Hospital Affiliated to China Medical University, Shenyang, , China
The First Hospital of China Medical University, Shenyang, , China
Tianjin Blood Disease Hospital, Tianjin, , China
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, , China
The affiliated hospital of Xuzhou medical university, Xuzhou, , China
Henan Cancer Hospital, Zhengzhou, , China
The first affiliated hospital of Zhengzhou University, Zhengzhou, , China
Contact Details
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
