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Brief Title: Randomised Controlled Phase-2 Trial to Determine the Efficacy of Adoptive Immunotherapy With NK Cells in High-risk AML
Official Title: Randomised Controlled Phase-2 Trial to Determine the Efficacy of Adoptive Immunotherapy With Haploidentical Natural Killer Cells in High-risk Acute Myeloid Leukemia
Study ID: NCT02229266
Brief Summary: The trial investigates the efficacy of adoptive immunotherapy with haploidentical natural killer cells compared to standard chemotherapy (after first complete remission) in patients with a high-risk acute myeloid leukemia being older than 65 years of age and not eligible for allogeneic transplantation
Detailed Description: Randomised controlled phase-2 trial to determine the efficacy of adoptive immunotherapy with haploidentical natural killer cells in high-risk acute myeloid leukemia
Minimum Age: 60 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Klinikum Bayreuth, Bayreuth, , Germany
Klinikum Chemnitz, Chemnitz, , Germany
Universitätsklinikum Dresden, Dresden, , Germany
Name: Martin Bornhäuser, Prof. Dr. med.
Affiliation: Universitätsklinikum Dresden
Role: PRINCIPAL_INVESTIGATOR