Spots Global Cancer Trial Database for Reduction of Cord Blood Transplantation Toxicity in Patients With Acute Myeloid Leukemia
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Trial Identification
Brief Title: Reduction of Cord Blood Transplantation Toxicity in Patients With Acute Myeloid Leukemia
Official Title: Assessment of Reduction of Cord Blood Transplantation Toxicity by Using Reduced Intensity Conditioning in Patients With Acute Myeloid Leukemia.
Study ID: NCT00797758
Conditions
Interventions
Study Description
Brief Summary: Multicentric evaluation of the reduction of unrelated cord blood transplantation (UCBT) toxicity by using reduced intensity conditioning (RIC) in patients with acute myeloid leukaemia.UCBT related mortality and morbidity were limiting factors for the development of this procedure in adults. Non myeloablative conditioning regimen showed promising results and prospective evaluation has to be developed to confirm these retrospective data.
Detailed Description: Individual meta-analysis is planned to compare geno-identical transplantation with myeloid-ablative or non myeloid-ablative conditioning with UCBT after RIC.
Eligibility
Minimum Age: 4 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Département d'Hématologie et d'Oncologie Médicale, Hôtel-Dieu, Paris, , France
Contact Details
Name: Bernard RIO, MD, PhD
Affiliation: Assistance Publique - Hôpitaux de Paris
Role: PRINCIPAL_INVESTIGATOR
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